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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 21, 2022; 28(31): 4363-4375
Published online Aug 21, 2022. doi: 10.3748/wjg.v28.i31.4363
Published online Aug 21, 2022. doi: 10.3748/wjg.v28.i31.4363
Application of computed tomography-based radiomics in differential diagnosis of adenocarcinoma and squamous cell carcinoma at the esophagogastric junction
Ke-Pu Du, Wen-Peng Huang, Yun-Jin Chen, Li-Ming Li, Yi-Jing Han, Yue Zhou, Chen-Chen Liu, Jian-Bo Gao, Department of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China
Si-Yun Liu, Department of Pharmaceutical Diagnostics, General Electric Company Healthcare, Beijing 100176, China
Xiao-Nan Liu, Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China
Author contributions: Du KP and Huang WP designed the research; Liu SY and Li LM performed the research; Chen YJ, Han YJ, Zhou Y, and Liu CC collected the data; Du KP and Huang WP analyzed the data and wrote the paper; Gao JB reviewed the paper; and all authors have read and approved the final manuscript.
Institutional review board statement: The study was approved by the Institutional Review Board at the First Affiliated Hospital of Zhengzhou University (No. 2021-ky-1070-002).
Conflict-of-interest statement: The authors declare that they have no competing interests to disclose.
Data sharing statement: All data generated or analyzed during this study are included in this published article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Bo Gao, PhD, Academic Research, Chairman, Chief Doctor, Instructor, Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 East Jianshe Road, Zhengzhou 450052, Henan Province, China.
Received: March 16, 2022
Peer-review started: March 16, 2022
First decision: June 11, 2022
Revised: June 11, 2022
Accepted: July 25, 2022
Article in press: July 25, 2022
Published online: August 21, 2022
Processing time: 153 Days and 2.1 Hours
Peer-review started: March 16, 2022
First decision: June 11, 2022
Revised: June 11, 2022
Accepted: July 25, 2022
Article in press: July 25, 2022
Published online: August 21, 2022
Processing time: 153 Days and 2.1 Hours
Core Tip
Core Tip: In this study, multiscale and multiphase computed tomography (CT)-based radiomics models were constructed and evaluated to discriminate squamous cell carcinoma and adenocarcinoma of the esophagogastric junction (CEGJ) before operation. The results demonstrated that the combination of multiphase 3D CT radiomics features could improve the differentiation performance than 2D CT radiomics or single-phase-based radiomics. Therefore, radiomics method could help open up a new field for noninvasive diagnosis and personalized management of CEGJ.