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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 7, 2022; 28(29): 3934-3945
Published online Aug 7, 2022. doi: 10.3748/wjg.v28.i29.3934
Published online Aug 7, 2022. doi: 10.3748/wjg.v28.i29.3934
Optimal timing of biliary drainage based on the severity of acute cholangitis: A single-center retrospective cohort study
Zhao-Qing Lu, Han-Yu Zhang, Chen-Fen Su, Yue-Yan Xing, Guo-Xing Wang, Department of Emergency Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
Chun-Sheng Li, Emergency and Critical Care Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
Author contributions: Li CS designed the research study and made critical revisions to the article; Lu ZQ, Zhang HY, Xing YY, Su CF, and Wang GX performed the research and analyzed the data; Lu ZQ drafted the article; all authors have read and approved the final manuscript.
Institutional review board statement: This retrospective cohort study was conducted according to the tenets of the Declaration of Helsinki, and approved by the Bioethics Committee of Beijing Friendship Hospital, Capital Medical University (Certification No. 2020-P2-224-01).
Informed consent statement: Since we conducted a retrospective review of patient data obtained from the electronic medical records of our hospital, and as stated by the ethical standards of China, the Ethics Committee exempted the need for obtaining informed consent.
Conflict-of-interest statement: All the Authors have no conflict of interest related to the manuscript.
Data sharing statement: The datasets used during the current study are available from the corresponding author on reasonable request at lcscyyy@163.com.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chun-Sheng Li, PhD, Professor, Emergency and Critical Care Center, Beijing Friendship Hospital, Capital Medical University, No. 95 Yongan Road, Xicheng District, Beijing 100050, China. lcscyyy@163.com
Received: March 17, 2022
Peer-review started: March 17, 2022
First decision: April 11, 2022
Revised: April 25, 2022
Accepted: July 5, 2022
Article in press: July 5, 2022
Published online: August 7, 2022
Processing time: 138 Days and 21.7 Hours
Peer-review started: March 17, 2022
First decision: April 11, 2022
Revised: April 25, 2022
Accepted: July 5, 2022
Article in press: July 5, 2022
Published online: August 7, 2022
Processing time: 138 Days and 21.7 Hours
Core Tip
Core Tip: This study aimed to investigate the optimal timing of drainage for patients with acute cholangitis (AC) with each grade and organ dysfunction. We first attempted to study whether AC patients with different organ dysfunction should undergo biliary drainage at distinct times. We believe that our study makes a significant contribution to the literature because we found that patients with severe AC should complete biliary decompression within 24 h of admission, while biliary drainage within 12 h was beneficial for AC patients with neurological or cardiovascular dysfunction.