Guo XW, Liang YX, Huang PY, Liang LX, Zeng YQ, Ding Z. Snare-assisted flexible endoscope in trans-gastric endoscopic gallbladder-preserving surgery: A pilot animal study. World J Gastroenterol 2022; 28(19): 2112-2122 [PMID: 35664034 DOI: 10.3748/wjg.v28.i19.2112]
Corresponding Author of This Article
Zhen Ding, PhD, Chief Doctor, Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. docd720@126.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Basic Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Xian-Wen Guo, Zhen Ding, Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China
Xian-Wen Guo, Yun-Xiao Liang, Peng-Yu Huang, Lie-Xin Liang, Yi-Qing Zeng, Department of Gastroenterology, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Author contributions: Guo XW and Ding Z contributed equally to this work; Guo XW and Ding Z were responsible for the study concept and design, including endoscopic procedures; all authors conducted the endoscopic operations together; Guo XW drafted the manuscript; Ding Z revised and finalized the manuscript.
Supported byNational Natural Science Foundation of China, No. 82060104; and Construction of Guangxi Clinical Medical Research Center for Digestive Diseases, No. AD17129027.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of the People's Hospital of Guangxi Zhuang Autonomous Region and the Ethics Committee of the Tongji Medical College, No. KY-LW-2019-4, [2020]-S322.
Institutional animal care and use committee statement: All procedures involving animals were reviewed and approved by the Institutional Animal Care and Use Committee of People's Hospital of Guangxi Zhuang Autonomous Region (No. KY-LW-2019-4) and the Institutional Animal Care and Committee at Huazhong University of Science and Technology Tongji Medical College (No. 2625).
Conflict-of-interest statement: To the best of our knowledge, no conflict of interest exists.
Data sharing statement: No additional data are available.
ARRIVE guidelines statement: The authors have read the ARRIVE guidelines, and the manuscript was prepared and revised according to the ARRIVE guidelines.
Corresponding author: Zhen Ding, PhD, Chief Doctor, Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. docd720@126.com
Received: December 19, 2021 Peer-review started: December 19, 2021 First decision: March 10, 2022 Revised: March 23, 2022 Accepted: April 15, 2022 Article in press: April 15, 2022 Published online: May 21, 2022 Processing time: 148 Days and 20.8 Hours
Core Tip
Core Tip: This study aimed to evaluate the feasibility and safety of a new surgical method, “snare-assisted pure natural orifice transluminal endoscopic surgery (NOTES) gallbladder-preserving surgery”. Eight miniature pigs were randomly divided into an experimental group [snare assisted (SA)] and a control group. The total operating time, gallbladder incision blood loss, gallbladder disorientation time, gallbladder incision closure time, and workload scores on the National Aeronautics and Space Administration-Task Load Index were significantly reduced in the SA group. These results indicated that snare-assisted pure NOTES gallbladder-preservation surgery reduced the difficulty of the operation, shortened the operation time, and did not increase complications.
