Vanella G, Tamburrino D, Capurso G, Bronswijk M, Reni M, Dell'Anna G, Crippa S, Van der Merwe S, Falconi M, Arcidiacono PG. Feasibility of therapeutic endoscopic ultrasound in the bridge-to-surgery scenario: The example of pancreatic adenocarcinoma. World J Gastroenterol 2022; 28(10): 976-984 [PMID: 35431499 DOI: 10.3748/wjg.v28.i10.976]
Corresponding Author of This Article
Paolo Giorgio Arcidiacono, FASGE, MD, Associate Professor, Director, Pancreatobiliary Endoscopy and EUS Division, Pancreas Translational & Clinical Research Center, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina, 60, Milan 20132, Italy. arcidiacono.paologiorgio@hsr.it
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Opinion Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Mar 14, 2022; 28(10): 976-984 Published online Mar 14, 2022. doi: 10.3748/wjg.v28.i10.976
Feasibility of therapeutic endoscopic ultrasound in the bridge-to-surgery scenario: The example of pancreatic adenocarcinoma
Giuseppe Vanella, Domenico Tamburrino, Gabriele Capurso, Michiel Bronswijk, Michele Reni, Giuseppe Dell'Anna, Stefano Crippa, Schalk Van der Merwe, Massimo Falconi, Paolo Giorgio Arcidiacono
Giuseppe Vanella, Gabriele Capurso, Giuseppe Dell'Anna, Paolo Giorgio Arcidiacono, Pancreatobiliary Endoscopy and EUS Division, Pancreas Translational & Clinical Research Center, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan 20132, Italy
Domenico Tamburrino, Stefano Crippa, Massimo Falconi, Pancreatic Surgery Unit, Pancreas Translational & Clinical Research Center, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan 20132, Italy
Michiel Bronswijk, Schalk Van der Merwe, Department of Gastroenterology and Hepatology, University Hospital Gasthuisberg, University of Leuven, Leuven 3000, Belgium
Michiel Bronswijk, Department of Gastroenterology and Hepatology, Imelda Hospital, Bonheiden 2820, Belgium
Michele Reni, Department of Medical Oncology, Pancreas Translational & Clinical Research Center, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy
Author contributions: Vanella G, Capurso G and Arcidiacono PG conceived the manuscript; Vanella G, Bronswijk M and Tamburrino D performed the literature search; Vanella G, Bronswijk M, Tamburrino D, Dell’Anna G and Capurso G drafted the paper; Arcidiacono PG, Reni M, Crippa S, Van der Merwe S and Falconi M critically revised the manuscript for important intellectual content; Vanella G created the figures; all authors agreed on the final submitted version, accepting to be accountable for accuracy or integrity of any part of the work.
Conflict-of-interest statement: Michiel Bronswijk has consultancy agreements with Prion Medical and Taewoong. Schalk van der Merwe holds the Cook Medical and Boston Scientific chair in Interventional Endoscopy and holds consultancy agreements with Cook Medical, Pentax and Olympus. The remaining authors declare no conflict of interest relevant for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Paolo Giorgio Arcidiacono, FASGE, MD, Associate Professor, Director, Pancreatobiliary Endoscopy and EUS Division, Pancreas Translational & Clinical Research Center, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina, 60, Milan 20132, Italy. arcidiacono.paologiorgio@hsr.it
Received: August 20, 2021 Peer-review started: August 20, 2021 First decision: October 2, 2021 Revised: October 4, 2021 Accepted: February 15, 2022 Article in press: February 15, 2022 Published online: March 14, 2022 Processing time: 202 Days and 11.4 Hours
Core Tip
Core Tip: Despite the increase of a subset of patients with pancreatic adenocarcinoma undergoing neoadjuvant chemotherapy, therapeutic endoscopic ultrasound (EUS) has been unfairly restricted in potentially resectable patients. However, to date, no evidence suggests any influence of therapeutic EUS procedures on difficulty or outcomes of eventual subsequent surgery. Conversely, proof-of-concept papers have described uncomplicated surgery following EUS-guided gallbladder drainage, choledochoduodenostomy and gastrojejunostomy. Available evidence and technical notes are collected in this review. Due to the very high efficacy-invasiveness ratio of therapeutic EUS procedures, potentially resulting in less chemotherapy discontinuation, we believe that their use should not be restricted in the bridge-to-surgery scenario while implementing its prospective evaluation.
