©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 7, 2021; 27(33): 5610-5621
Published online Sep 7, 2021. doi: 10.3748/wjg.v27.i33.5610
Published online Sep 7, 2021. doi: 10.3748/wjg.v27.i33.5610
Radiomics for predicting perineural invasion status in rectal cancer
Mou Li, Yu-Mei Jin, Sheng-Mei Liu, Bin Song, Department of Radiology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Yong-Chang Zhang, Department of Radiology, Chengdu Seventh People’s Hospital, Chengdu 610213, Sichuan Province, China
Ya-Li Zhao, Chen-Cui Huang, Department of Research Collaboration, R&D Center, Beijing Deepwise & League of PHD Technology Co., Ltd, Beijing 100080, China
Author contributions: Song B and Li M designed the research; Jin YM and Liu SM collected the data; Li M, Zhang YC, Zhao YL, and Huang CC analyzed the data; Li M and Song B wrote the paper; all authors have read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of West China Hospital of Sichuan University (Approved No.1159).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: Zhao YL and Huang CC are employed by the company Beijing Deepwise & League of PHD Technology Co., Ltd. The remaining authors declare no conflicts-of-interest related to this article.
Data sharing statement: No additional data are available.
Corresponding author: Bin Song, MD, Chief Doctor, Professor, Department of Radiology, West China Hospital of Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, Sichuan Province, China. songlab_radiology@163.com
Received: June 2, 2021
Peer-review started: June 2, 2021
First decision: June 25, 2021
Revised: July 3, 2021
Accepted: August 11, 2021
Article in press: August 11, 2021
Published online: September 7, 2021
Processing time: 93 Days and 7.9 Hours
Peer-review started: June 2, 2021
First decision: June 25, 2021
Revised: July 3, 2021
Accepted: August 11, 2021
Article in press: August 11, 2021
Published online: September 7, 2021
Processing time: 93 Days and 7.9 Hours
Core Tip
Core Tip: In this study, a radiomics model integrating Rad-score and clinical factors was developed and validated for predicting perineural invasion status in patients with rectal cancer. Radiomics features were extracted from intra- and peritumoral regions. This radiomics model showed good performance and outperformed the clinical factors. Therefore, the combined model might assist in predicting perineural invasion status and improving prognosis of patients with rectal cancer.