Potential risk factors for constipation in the community

doi:10.3748/wjg.v27.i21.2795

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 7, 2021; 27(21): 2795-2817
Published online Jun 7, 2021. doi: 10.3748/wjg.v27.i21.2795

Potential risk factors for constipation in the community

Barry L Werth, Sybele-Anne Christopher

Barry L Werth, Sybele-Anne Christopher, Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, University of Sydney, Sydney 2006, New South Wales, Australia

Author contributions: Werth BL designed the review and wrote the original draft of the manuscript which was reviewed and edited by Christopher SA. Further versions of the manuscript were reviewed and edited by both authors; both authors approved the final version of the manuscript.

Conflict-of-interest statement: The authors declare no conflict of interest regarding publication of this review.

Corresponding author: Barry L Werth, BPharm, MBA, PhD, Pharmacist, Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, University of Sydney, Building Western Avenue, Sydney 2006, New South Wales, Australia. barrywerth@yahoo.com.au

Received: January 27, 2021
Peer-review started: January 27, 2021
First decision: February 27, 2021
Revised: March 31, 2021
Accepted: April 26, 2021
Article in press: April 26, 2021
Published online: June 7, 2021
Processing time: 120 Days and 8.8 Hours

Core Tip

Core Tip: Despite widespread beliefs that there are a number of potential risk factors for constipation in the community, this review highlights the paucity of real-world evidence for most factors. It is unclear whether most factors are associated with constipation because, apart from female gender, physical activity, residential location and some health-related factors, there is insufficient evidence or conflicting data available. Further research is required in community-dwelling adult populations to understand the importance of each potential risk factor in constipation. A broad range of factors should be investigated in same population samples using multivariate analysis to determine which factors are truly associated with constipation in the community.