Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 21, 2021; 27(11): 1055-1063
Published online Mar 21, 2021. doi: 10.3748/wjg.v27.i11.1055
Study on the characteristics of intestinal motility of constipation in patients with Parkinson's disease
Mei Zhang, Shuang Yang, Xiao-Cui Li, Hong-Ming Zhu, Ding Peng, Bang-Yi Li, Tian-Xu Jia, Chen Tian
Mei Zhang, Shuang Yang, Xiao-Cui Li, Hong-Ming Zhu, Ding Peng, Bang-Yi Li, Tian-Xu Jia, Chen Tian, Department of Gastroenterology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
Mei Zhang, National Clinical Research Center for Geriatric Disease, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
Author contributions: Zhang M designed the research and wrote the paper; Yang S and Li XC performed the research; Li BY and Peng D analyzed the data; Jia TX and Tian C collected the data; all authors approved the final version.
Institutional review board statement: Institutional review board statement: This survey was reviewed and approved by the Ethics Committee of the Xuanwu Hospital of Capital Medical University.
Informed consent statement: The research subjects of this survey have fully understood and agreed to the research content.
Conflict-of-interest statement: The authors declare no conflict of interest regarding the manuscript.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mei Zhang, PhD, Chief Physician, Doctor, Professor, Department of Gastroenterology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun street, Xuanwu District, Beijing 100053, China. zhang2955@sina.com
Received: January 26, 2021
Peer-review started: January 26, 2021
First decision: February 8, 2021
Revised: February 14, 2021
Accepted: March 8, 2021
Article in press: March 8, 2021
Published online: March 21, 2021
Processing time: 49 Days and 20.6 Hours
Core Tip

Core Tip: In this study, we used the colonic transit test and rectal anal manometry to subtype constipation and detect corresponding indicators in patients with Parkinson's disease with constipation (PDC) and functional constipation, with the aim of clarifying the colonic and rectal motility characteristics of PDC and providing a basis for the treatment of PDC. It was found that the segmental colonic transit time and the constituent ratio of types of defecation disorders were statistically different between the two groups.