Su Hyuk Ko, Jong Ik Jeon, Jung Mogg Kim, Department of Microbiology and Department of Biomedical Science, Hanyang University College of Medicine and Graduate School of Biomedical Science and Engineering, Seoul 04763, South Korea
Hyun Ae Woo, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, South Korea
Author contributions: Ko SH performed the majority of experiments and analyzed the data; Jeon JI performed the molecular investigations; Woo HA participated equally in treatment of animals; Kim JM designed and coordinated the research; Ko SH and Kim JM wrote the manuscript; all authors approved the final version of the article.
Institutional animal care and use committee statement: All animal experiments were performed according to protocols approved by the Institutional Animal Care and Use Committee of Hanyang University and Ewha Womans University (IACUC No. 2013-0197A and IACUC No. 17-012).
Conflict-of-interest statement: None of the authors of this study has any conflicts of interest.
Data sharing statement: No additional data are available.
ARRIVE guidelines statement: The authors have read the ARRIVE guidelines, and the manuscript was prepared and revised according to the ARRIVE guidelines.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jung Mogg Kim, MD, PhD, Chairman, Director, Doctor, Professor, Department of Microbiology, Hanyang University College of Medicine, 222 Wangsimni-ro, Seongdong-gu, Seoul 04763, South Korea.
jungmogg@hanyang.ac.kr
Supported by the Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology, South Korea, No. NRF-2018R1D1A1B07043350.
Received: October 28, 2019
Peer-review started: October 28, 2019
First decision: December 12, 2019
Revised: December 20, 2019
Accepted: January 11, 2020
Article in press: January 11, 2020
Published online: January 21, 2020
Processing time: 79 Days and 20.6 Hours
