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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 14, 2020; 26(22): 3000-3011
Published online Jun 14, 2020. doi: 10.3748/wjg.v26.i22.3000
Published online Jun 14, 2020. doi: 10.3748/wjg.v26.i22.3000
Diagnostic challenges in non-cirrhotic portal hypertension - porto sinusoidal vascular disease
Oana Nicoară-Farcău, Ioana Rusu, Marcel Tanțău, Radu Ion Badea, Bogdan Procopeț, University of Medicine and Pharmacy “Iuliu Hatieganu”, Cluj-Napoca 400000, Romania
Oana Nicoară-Farcău, Horia Stefănescu, Marcel Tanțău, Bogdan Procopeț, Gastroenterology Department, Regional Institute of Gastroenterology and Hepatology “O. Fodor”, Cluj-Napoca 400000, Romania
Ioana Rusu, Pathology Department, Regional Institute of Gastroenterology and Hepatology “O. Fodor”, Cluj-Napoca 400000, Romania
Radu Ion Badea, Imagistic Department, Regional Institute of Gastroenterology and Hepatology “O. Fodor”, Cluj-Napoca 400000, Romania
Author contributions: Nicoară-Farcău O and Rusu I drafted the manuscript and prepared the figures and tables; Stefănescu H revised the first draft of the manuscript and provided input in the writing; Tanțău M and Badea RI revised the manuscript and provided input in the writing; Procopeț B coordonanted the writing of the manuscript, revised the manuscript and validated the final version of the manuscript.
Supported by UEFISCDI , Ministry of Education of Romania, No. PN-III-P1-1.1-PD-2016-0689.
Conflict-of-interest statement: Authors declare no potential conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Bogdan Procopeț, MD, PhD, Doctor, Senior Lecturer, Staff Physician, Gastroenterology and Hepatology Department, 3rd Medical Clinic, University of Medicine and Pharmacy “Iuliu Hatieganu”, 19-21 Croitorilor Street, Cluj-Napoca 400162, Romania. bogdan.procopet@umfcluj.ro
Received: December 30, 2019
Peer-review started: December 30, 2019
First decision: February 16, 2020
Revised: March 31, 2020
Accepted: May 27, 2020
Article in press: May 27, 2020
Published online: June 14, 2020
Processing time: 166 Days and 14.8 Hours
Peer-review started: December 30, 2019
First decision: February 16, 2020
Revised: March 31, 2020
Accepted: May 27, 2020
Article in press: May 27, 2020
Published online: June 14, 2020
Processing time: 166 Days and 14.8 Hours
Core Tip
Core tip: Non-cirrhotic portal hypertension consists of a group of diseases characterized by signs and complications of portal hypertension. However, their diagnosis is sometimes difficult due to their similarities in clinical presentation, imaging signs and histological modifications despite advances in their understanding. Moreover, these disorders are sometimes misdiagnosed as cirrhosis. This review highlights their diagnostic challenges, especially with regard to porto sinusoidal vascular disease, extrahepatic portal vein obstruction, sinusoidal obstruction syndrome and cirrhosis and discusses the current available diagnostic tools.