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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 14, 2020; 26(10): 995-1004
Published online Mar 14, 2020. doi: 10.3748/wjg.v26.i10.995
Published online Mar 14, 2020. doi: 10.3748/wjg.v26.i10.995
Global whole family based-Helicobacter pylori eradication strategy to prevent its related diseases and gastric cancer
Song-Ze Ding, Department of Gastroenterology and Hepatology, People’s Hospital of Zhengzhou University, Henan Provincial People’s Hospital, and Henan University School of Medicine, Zhengzhou 450003, Henan Province, China
Author contributions: Ding SZ designed the overall concept and outline of the manuscript; completed the writing, editing the manuscript, illustrations, and review of literature.
Supported by grants to SZD from Henan Provincial Government-Science and Technology Bureau , No. 142300410050 ; Henan Provincial Government-Health and Family Planning Commission , No. 20170123 ; Henan Provincial Innovative Talents Projects of 2016 and 2017 ; National Natural Science Foundation of China , No. U1604174 .
Conflict-of-interest statement: The author declares no conflicts of interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Song-Ze Ding, MD, PhD, Chief Doctor, Full Professor, Department of Gastroenterology and Hepatology, Henan Provincial People’s Hospital, Zhengzhou University, No. 7 Wei Wu Road, Jin Shui District, Zhengzhou 450003, Henan Province, China. dingsongze@hotmail.com
Received: November 14, 2019
Peer-review started: November 14, 2019
First decision: December 4, 2019
Revised: December 14, 2019
Accepted: February 12, 2020
Article in press: February 12, 2020
Published online: March 14, 2020
Processing time: 121 Days and 1.6 Hours
Peer-review started: November 14, 2019
First decision: December 4, 2019
Revised: December 14, 2019
Accepted: February 12, 2020
Article in press: February 12, 2020
Published online: March 14, 2020
Processing time: 121 Days and 1.6 Hours
Core Tip
Core tip: Helicobacter pylori (H. pylori) infection is an infectious and family-based disease. In additional to “test and treat” and "screen and treat" strategies, this work introduces a novel, “whole family-based H. pylori eradication strategy” to screen, identify, treat and follow up on all H. pylori-infected family members within a family unit. This “whole family- or household-based strategy” is high-risk population-oriented, and will be able to reduce H. pylori spreading among family members with good patient-family compliance. Importantly, this strategy is practical for both high and low H. pylori-infected communities.