©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 28, 2019; 25(8): 909-922
Published online Feb 28, 2019. doi: 10.3748/wjg.v25.i8.909
Published online Feb 28, 2019. doi: 10.3748/wjg.v25.i8.909
Outcomes of per oral endoscopic pyloromyotomy in gastroparesis worldwide
Parit Mekaroonkamol, Rushikesh Shah, Qiang Cai, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, GA 30322, United States
Author contributions: All authors have contributed to this study.
Conflict-of-interest statement: All the Authors have no conflict of interest related to the manuscript.
Corresponding author: Qiang Cai, MD, PhD, Professor, Division of Digestive Diseases, Emory University School of Medicine, 1365 Clifton Road, B1262, Atlanta, GA 30322, United States. qcai@emory.edu
Telephone: +1-4047782714 Fax: +1-4047782578
Received: October 30, 2018
Peer-review started: November 1, 2018
First decision: November 29, 2018
Revised: January 10, 2019
Accepted: January 26, 2019
Article in press: January 26, 2019
Published online: February 28, 2019
Processing time: 121 Days and 8.4 Hours
Peer-review started: November 1, 2018
First decision: November 29, 2018
Revised: January 10, 2019
Accepted: January 26, 2019
Article in press: January 26, 2019
Published online: February 28, 2019
Processing time: 121 Days and 8.4 Hours
Core Tip
Core tip: Per oral endoscopic pyloromyotomy (POP), or gastric per oral endoscopic myotomy is a viable therapeutic modality for patients with medically refractory gastroparesis. POP has demonstrated promising mid-term clinic outcomes in up to 18 mo follow-up period. However, most published studies were single-center and retrospective. Duration of the disease, prior response to intrapyloric botulinum injection, and increased pyloric cross-sectional area has been described as predictive factors for POP outcome. Impedance planimetry can be used to evaluate pyloric dysfunction. However, the reliability of these factors still needs clinical validation.