©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 28, 2019; 25(28): 3738-3752
Published online Jul 28, 2019. doi: 10.3748/wjg.v25.i28.3738
Published online Jul 28, 2019. doi: 10.3748/wjg.v25.i28.3738
Current approaches to the management of patients with cirrhotic ascites
Dmitry Victorovich Garbuzenko, Department of Faculty Surgery, South Ural State Medical University, Chelyabinsk 454092, Russia
Nikolay Olegovich Arefyev, Department of Pathological Anatomy and Forensic Medicine, South Ural State Medical University, Chelyabinsk 454092, Russia
Author contributions: Garbuzenko DV contributed to the conception, design, acquisition, analysis, interpretation of data, wrote the manuscript and approved the final version; Arefyev NO contributed to analysis of data, wrote and revised the manuscript, generated the figures, and approved the final version.
Conflict-of-interest statement: The authors have nothing to disclose.
Corresponding author: Dmitry Victorovich Garbuzenko, MD, PhD, Professor, Department of Faculty Surgery, South Ural State Medical University, PO Box 12317, Chelyabinsk 454080, Russia. garb@inbox.ru
Telephone: +7-909-7459826 Fax: +7-351-2687772
Received: April 16, 2019
Peer-review started: April 16, 2019
First decision: April 30, 2019
Revised: May 9, 2019
Accepted: June 25, 2019
Article in press: June 26, 2019
Published online: July 28, 2019
Processing time: 103 Days and 16.1 Hours
Peer-review started: April 16, 2019
First decision: April 30, 2019
Revised: May 9, 2019
Accepted: June 25, 2019
Article in press: June 26, 2019
Published online: July 28, 2019
Processing time: 103 Days and 16.1 Hours
Core Tip
Core tip: This review describes current approaches to the management of patients with cirrhotic ascites in relation to the severity of its clinical manifestations. The literature analysis has shown that despite the achievements of modern hepatology, the presence of ascites is associated with poor prognosis and high mortality. The key to successful management of patients with ascites may be the stratification of the risk of an adverse outcome and personalized therapy. Pathogenetically based approach to the choice of pharmacotherapy and optimization of minimally invasive methods of treatment may improve the quality of life and increase the survival rate of this category of patients.