©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 21, 2018; 24(47): 5312-5321
Published online Dec 21, 2018. doi: 10.3748/wjg.v24.i47.5312
Published online Dec 21, 2018. doi: 10.3748/wjg.v24.i47.5312
Split liver transplantation: Current developments
Christina Hackl, Katharina M Schmidt, Martin Zidek, Hans J Schlitt, Department of Surgery, University Hospital Regensburg, Regensburg 93053, Germany
Caner Süsal, Bernd Döhler, Collaborative Transplant Study (CTS), Institute of Immunology, Heidelberg University, Heidelberg 69120, Germany
Author contributions: Hackl C contributed to conception and design, acquisition of data, drafting the article, critical revision for important intellectual content, and final approval of the version to be published; Schmidt KM and Zidek M contributed to conception and design, critical revision for important intellectual content, and final approval of the version to be published; Süsal C and Döhler B contributed to acquisition of data, critical revision for important intellectual content, and final approval of the version to be published; Schlitt HJ contributed to conception and design, acquisition of data, drafting the article, critical revision for important intellectual content, and final approval of the version to be published.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Corresponding author to: Christina Hackl, MD, Department of Surgery, University Medical Center Regensburg, Franz Josef Strauss Allee 11, Regensburg 93053, Germany. christina.hackl@ukr.de
Telephone: +49-941-94416806 Fax: +49-941-9446802
Received: July 9, 2018
Peer-review started: July 10, 2018
First decision: July 18, 2018
Revised: October 9, 2018
Accepted: October 21, 2018
Article in press: October 21, 2018
Published online: December 21, 2018
Processing time: 167 Days and 13.4 Hours
Peer-review started: July 10, 2018
First decision: July 18, 2018
Revised: October 9, 2018
Accepted: October 21, 2018
Article in press: October 21, 2018
Published online: December 21, 2018
Processing time: 167 Days and 13.4 Hours
Core Tip
Core tip: As of today, split liver transplantation (SLT) is a widely adopted but yet technically demanding approach to enable liver transplantation especially in very young recipients, and to reduce organ shortage and waitlist mortality. In contrast to full organ liver transplantation, many technical evaluations concerning the donor organ, the recipient, as well as the splitting procedure and the organ allocation policy, must be considered before a SLT can safely be performed. The present review gives insight into current controversies, technical challenges, and clinical outcomes of SLT.