Zhang YF, Ji H, Lu HW, Lu L, Wang L, Wang JL, Li YM. Postoperative survival analysis and prognostic nomogram model for patients with portal hypertension. World J Gastroenterol 2018; 24(39): 4499-4509 [PMID: 30356927 DOI: 10.3748/wjg.v24.i39.4499]
Corresponding Author of This Article
Yi-Ming Li, MD, Professor, Department of General Surgery, the Second Affiliated Hospital of Xi’an Jiaotong University, No. 157, Xiwu Road, Xi’an 710004, Shaanxi Province, China. liyiming@xjtu.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
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Zhang YF, Ji H, Lu HW, Lu L, Wang L, Wang JL, Li YM. Postoperative survival analysis and prognostic nomogram model for patients with portal hypertension. World J Gastroenterol 2018; 24(39): 4499-4509 [PMID: 30356927 DOI: 10.3748/wjg.v24.i39.4499]
World J Gastroenterol. Oct 21, 2018; 24(39): 4499-4509 Published online Oct 21, 2018. doi: 10.3748/wjg.v24.i39.4499
Postoperative survival analysis and prognostic nomogram model for patients with portal hypertension
Ya-Fei Zhang, Hong Ji, Hong-Wei Lu, Le Lu, Lei Wang, Jin-Long Wang, Yi-Ming Li
Ya-Fei Zhang, Hong Ji, Hong-Wei Lu, Le Lu, Lei Wang, Jin-Long Wang, Yi-Ming Li, Department of General Surgery, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, China
Author contributions: Li YM conceived the research and critically reviewed and revised the paper; Zhang YF, Ji H, Lu HW and Lu L designed the research and analysed the data; Zhang YF and Li YM performed the research; all authors participated in the operations; Zhang YF drafted the paper.
Supported bythe National Natural Science Foundation of China, No. 81170454, No. 30772049 and No. 30571765.
Institutional review board statement: The study was reviewed and approved by the Second Affiliated Hospital of Xi’an Jiaotong University Institutional Review Board.
Informed consent statement: The requirement for written informed patient consent was waived due to the retrospective and anonymous nature of this study; all data were used only for statistical analysis.
Conflict-of-interest statement: All authors declare no conflicts of interest related to this study.
Data sharing statement: No additional data are available.
Correspondence to: Yi-Ming Li, MD, Professor, Department of General Surgery, the Second Affiliated Hospital of Xi’an Jiaotong University, No. 157, Xiwu Road, Xi’an 710004, Shaanxi Province, China. liyiming@xjtu.edu.cn
Telephone: +86-29-87679746 Fax: +86-29-87679746
Received: August 8, 2018 Peer-review started: August 8, 2018 First decision: August 30, 2018 Revised: September 6, 2018 Accepted: October 5, 2018 Article in press: October 5, 2018 Published online: October 21, 2018 Processing time: 71 Days and 20.1 Hours
Core Tip
Core tip: The mortality and re-bleeding rate are still extremely high among patients with portal hypertension after splenectomy plus pericardial devascularisation. This study aimed to analyse the postoperative survival, identify risk factors, construct nomograms, and explore the clinical effect of splenectomy plus simplified pericardial devascularisation (SSPD). Five hundred and fifty-seven (53.30%) patients were successfully followed, and the results suggested that the 5- and 10-year overall survival, disease-specific survival and bleeding-free survival rates were not significantly different between patients who underwent SSPD and patients who underwent splenectomy plus traditional pericardial devascularisation. Age, operative time, alanine transaminase level and albumin-bilirubin score were independent prognostic factors influencing overall survival. Male sex, age, intraoperative blood loss and time to first flatus were independent prognostic factors influencing bleeding-free survival. Comprehensive Complication Index and age were independent prognostic factors influencing disease-specific survival.
