Endoscopic diagnosis of sessile serrated adenoma/polyp with and without dysplasia/carcinoma

Core Tip

Core tip: The endoscopic features of sessile serrated adenoma/polyps (SSA/Ps) with and without dysplasia/carcinoma are reviewed. Conventional endoscopic characteristics, including a proximal location, a slightly elevated morphology, a pale color, and a mucus cap, are useful for diagnosing SSA/Ps. Magnifying narrow-band imaging, which detects dark spots inside the crypts and varicose microvascular vessels, and magnifying chromoendoscopy, which identifies the type II-open pit pattern, are also effective for differentiating between SSA/Ps and hyperplastic polyps. Furthermore, the lesions’ endoscopic characteristics, which include their (semi)pedunculated morphologies, double elevations, central depressions, and reddishness, and the use of magnifying endoscopy, might help to detect dysplasia/carcinoma within SSA/Ps.