©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 14, 2017; 23(6): 949-956
Published online Feb 14, 2017. doi: 10.3748/wjg.v23.i6.949
Published online Feb 14, 2017. doi: 10.3748/wjg.v23.i6.949
Lymphocytic esophagitis: Still an enigma a decade later
Carol Rouphael, Department of General Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, United States
Ilyssa O Gordon, Department of Pathology, Cleveland Clinic Foundation, Cleveland, OH 44195, United States
Prashanthi N Thota, Department of Gastroenterology and Hepatology, Digestive Disease and Surgery Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, United States
Author contributions: All authors contributed to this paper with conception and design of the study, literature review and analysis, drafting, revision and final approval of the manuscript.
Conflict-of-interest statement: All authors have no conflict of interest.
Correspondence to: Prashanthi N Thota, MD, FACG, Director, Esophageal Center, Department of Gastroenterology and Hepatology, Digestive Disease and Surgery Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, United States. thotap@ccf.org
Telephone: +1-216-4440780 Fax: +1-216-4454222
Received: October 24, 2016
Peer-review started: October 27, 2016
First decision: December 2, 2016
Revised: December 14, 2016
Accepted: January 18, 2017
Article in press: January 18, 2017
Published online: February 14, 2017
Processing time: 111 Days and 7.1 Hours
Peer-review started: October 27, 2016
First decision: December 2, 2016
Revised: December 14, 2016
Accepted: January 18, 2017
Article in press: January 18, 2017
Published online: February 14, 2017
Processing time: 111 Days and 7.1 Hours
Core Tip
Core tip: Lymphocytic esophagitis has recently been described in 2006 and subsequently, multiple groups have attempted to describe its clinical associations and risk factors with minimal information available on treatment. We performed a PubMed search of all case reports and retrospective studies published in English about lymphocytic esophagitis. The objective of this paper is to present a scientific review of all aspects of this emerging clinical entity known to date.