Case Report
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 28, 2017; 23(44): 7939-7944
Published online Nov 28, 2017. doi: 10.3748/wjg.v23.i44.7939
First case of cross-auxiliary double domino donor liver transplantation
Zhi-Jun Zhu, Lin Wei, Wei Qu, Li-Ying Sun, Ying Liu, Zhi-Gui Zeng, Liang Zhang, En-Hui He, Hai-Ming Zhang, Ji-Dong Jia, Zhong-Tao Zhang
Zhi-Jun Zhu, Lin Wei, Wei Qu, Li-Ying Sun, Ying Liu, Zhi-Gui Zeng, Liver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
Zhi-Jun Zhu, Lin Wei, Wei Qu, Li-Ying Sun, Ying Liu, Zhi-Gui Zeng, Liang Zhang, En-Hui He, Hai-Ming Zhang, Ji-Dong Jia, Zhong-Tao Zhang, National Clinical Research Center for Digestive Diseases, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
Zhi-Jun Zhu, Li-Ying Sun, Beijing Key Laboratory of Tolerance Induction and Organ Protection in Transplantation, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
Author contributions: Zhu ZJ planned and performed the operations; Wei L, Qu W and Zeng ZG participated in the operations; Wei L, Qu W, Sun LY and Liu Y performed the patient management after the operations; Qu W and Liu Y followed the patients after discharge; He EH monitored the blood flow by ultrasound; Zhang HM and Zhu ZJ wrote the case report; Jia JD and Zhang ZT contributed to the treatments and operations as expert consultants; all authors contributed to this article.
Supported by Capital Special Program for Health Research and Development, No. 2016-1-2021; National Key Technologies R&D Program, No. 2015BAI13B09; The Training Program of Academic Leaders in Beijing Health System, No. 2014-2-002; Beijing Municipal Administration of Hospitals Ascent Plan, No. DFL20150101.
Institutional review board statement: This work was approved by the Ethics Committee of Beijing Friendship Hospital.
Informed consent statement: Written consent for the operations and the voluntary disclosure of personal data was obtained.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to disclose.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Zhi-Jun Zhu, MD, Liver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China. zhu-zhijun@outlook.com
Telephone: +86-10-63138350 Fax: +86-10-63138350
Received: August 7, 2017
Peer-review started: August 8, 2017
First decision: September 6, 2017
Revised: September 22, 2017
Accepted: October 27, 2017
Article in press: October 27, 2017
Published online: November 28, 2017
Processing time: 111 Days and 15.7 Hours
Core Tip

Core tip: We implanted two domino graft livers into a familial amyloid polyneuropathy patient. One domino graft liver was from a child with Wilson’s disease, and the other was from a child with ornithine carbamyl enzyme defect. The blood flows of the two grafts were balanced by a percutaneous transcatheter selective portal vein embolization. These two domino donor grafts from donors with different metabolic disorders restored normal liver function. Our experience demonstrated a new approach to resolving metabolic disorders with domino grafts and utilizing explanted livers from children.