Copyright
©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 14, 2017; 23(30): 5602-5609
Published online Aug 14, 2017. doi: 10.3748/wjg.v23.i30.5602
Published online Aug 14, 2017. doi: 10.3748/wjg.v23.i30.5602
Combination of acoustic radiation force impulse imaging, serological indexes and contrast-enhanced ultrasound for diagnosis of liver lesions
Xiao-Lan Sun, Department of Ultrasound, Shanghai Yangpu District East Hospital, Shanghai 200433, China
Hui Yao, Department of Radiotherapy, Shanghai Yangpu District East Hospital, Shanghai 200433, China
Qiong Men, Department of Oncology, Shanghai Yangpu District East Hospital, Shanghai 200433, China
Ke-Zhu Hou, Department of Surgery, Shanghai Yangpu District East Hospital, Shanghai 200433, China
Zhen Chen, Department of Pathology, Shanghai Yangpu District East Hospital, Shanghai 200433, China
Chang-Qing Xu, Department of Radiography, Shanghai Yangpu District East Hospital, Shanghai 200433, China
Li-Wei Liang, Department of Gastroenterology, Shanghai Yangpu District East Hospital, Shanghai 200433, China
Author contributions: Sun XL and Liang LW designed the research; Sun XL, Yao H, Men Q, Hou KZ and Liang LW performed the research; Sun XL, Yao H, Men Q, Hou KZ, Chen Z, Xu CQ and Liang LW contributed new reagents or analytic tools; Sun XL, Hou KZ, Chen Z, Xu CQ and Liang LW analyzed the data; Sun XL and Liang LW wrote the paper.
Supported by Yangpu District Health and Family Planning Commission , Yangpu District Science and Technology Commission, No. YP15M18 ; Research Project of Shanghai Municipal Commission of Health and Family Planning , No. 201540032 .
Institutional review board statement: This study was approved by Shanghai Yangpu District East Hospital Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article are reported.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Li-Wei Liang, Attending Physician, Department of Gastroenterology, Shanghai Yangpu District East Hospital, No. 999 Shiguang Road, Yangpu District, Shanghai 200433, China. ypsdkjk@163.com
Telephone: +86-21-65881977
Received: March 27, 2017
Peer-review started: March 29, 2017
First decision: April 11, 2017
Revised: April 24, 2017
Accepted: May 9, 2017
Article in press: May 9, 2017
Published online: August 14, 2017
Processing time: 139 Days and 11.3 Hours
Peer-review started: March 29, 2017
First decision: April 11, 2017
Revised: April 24, 2017
Accepted: May 9, 2017
Article in press: May 9, 2017
Published online: August 14, 2017
Processing time: 139 Days and 11.3 Hours
Core Tip
Core tip: This study investigated the diagnostic value of combined acoustic radiation force impulse (ARFI) imaging, serological indicators and contrast-enhanced ultrasound in differentiating between benign and malignant liver lesions. The results showed that the diagnostic performance of combined ARFI, alpha-fetoprotein (AFP) and contrast-enhanced ultrasound in distinguishing between benign and malignant liver lesions was higher than the use of any single parameter or the combination of any two of parameters. It is expected that this would provide a tool for the differential diagnosis of benign and malignant liver lesions.