Bor S, Kitapcioglu G, Kasap E. Prevalence of gastroesophageal reflux disease in a country with a high occurrence of Helicobacter pylori. World J Gastroenterol 2017; 23(3): 525-532 [PMID: 28210089 DOI: 10.3748/wjg.v23.i3.525]
Corresponding Author of This Article
Serhat Bor, MD, Section of Gastroenterology, Ege Reflux Group, Ege University, Ege Universitesi Tip Fakultesi, Gastroenteroloji, Bornova, Izmir 35040, Turkey. serhatbor@yahoo.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Observational Study
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Bor S, Kitapcioglu G, Kasap E. Prevalence of gastroesophageal reflux disease in a country with a high occurrence of Helicobacter pylori. World J Gastroenterol 2017; 23(3): 525-532 [PMID: 28210089 DOI: 10.3748/wjg.v23.i3.525]
World J Gastroenterol. Jan 21, 2017; 23(3): 525-532 Published online Jan 21, 2017. doi: 10.3748/wjg.v23.i3.525
Prevalence of gastroesophageal reflux disease in a country with a high occurrence of Helicobacter pylori
Serhat Bor, Gul Kitapcioglu, Elmas Kasap
Serhat Bor, Section of Gastroenterology, Ege Reflux Group, Ege University, Izmir 35040, Turkey
Gul Kitapcioglu, Department of Biostatistics, Ege Reflux Group, Ege University, Izmir 35040, Turkey
Elmas Kasap, Section of Gastroenterology, Celal Bayar University, Manisa 45030, Turkey
Author contributions: Bor S, Kitapcioglu G and Kasap E conceptioned and designed of the study; Generation, collection, assembly, interpretation of data, Drafting or revision of the manuscript, approval of the final version of the manuscript; Kitapcioglu G analysis and/or interpretation of data, approval of the final version of the manuscript; Kasap E Generation, collection, assembly, interpretation of data, approval of the final version of the manuscript.
Supported byThis study partially support from Sanovel, Turkey.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No additional data are available.
Correspondence to: Serhat Bor, MD, Section of Gastroenterology, Ege Reflux Group, Ege University, Ege Universitesi Tip Fakultesi, Gastroenteroloji, Bornova, Izmir 35040, Turkey. serhatbor@yahoo.com
Telephone: +90-532-3957677 Fax: +90-232-3731547
Received: August 13, 2016 Peer-review started: August 14, 2016 First decision: September 5, 2016 Revised: October 4, 2016 Accepted: December 2, 2016 Article in press: December 2, 2016 Published online: January 21, 2017 Processing time: 154 Days and 9.8 Hours
Core Tip
Core tip: Using a validated gastroesophageal reflux disease (GERD) questionnaire and the urea breath test for Helicobacter pylori (H. pylori), we found a relatively high prevalence of GERD and more frequent regurgitation than heartburn. We also determined that the prevalence of GERD increases with increased body mass index and with female gender and decreases with increased education and income, whereas there was no relationship with age, alcohol use, or smoking. Additionally, we found that H. pylori did not affect the prevalence or symptom profile of GERD and that Turkish individual with classical symptoms were more prone to additional symptoms. This unique disease profile may be attributable to Turkey's combination of Western and Eastern lifestyles.
