©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 21, 2017; 23(3): 516-524
Published online Jan 21, 2017. doi: 10.3748/wjg.v23.i3.516
Published online Jan 21, 2017. doi: 10.3748/wjg.v23.i3.516
Clinicopathological, treatment, and prognosis study of 43 gastric neuroendocrine carcinomas
De-Jun Liu, Xue-Liang Fu, Wei Liu, Jun-Feng Zhang, Yan-Miao Huo, Jiao Li, Rong Hua, Yong-Wei Sun, Department Biliary-Pancreatic Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
Lu-Ying Zheng, Qiang Liu, Department Pathology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
Author contributions: Liu DJ, Fu XL and Liu W wrote the paper; Zheng LY, Zhang JF, Huo YM and Li J collected the data; Liu DJ, Fu XL, Liu W and Zheng LY performed the data analysis; Hua R, Liu Q and Sun YW designed the study and revised the paper; all authors have read and approved the final version to be published.
Supported by Chinese Society of Clinical Oncology , No. Y-N2013-014 .
Institutional review board statement: The research was approved by the Research Ethics Committee of Ren Ji Hospital and comply with ethical standards.
Informed consent statement: Due to the retrospective nature of the study, patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to receive surgery, postoperative chemotherapy and the other medical treatment by written informed consent.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: No additional data are available
Correspondence to: Yong-Wei Sun, PhD, Biliary-Pancreatic Surgery Department, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, No 1630 Dong Fang Road, Shanghai 200127, China. syw0616@yeah.net
Telephone: +86-21-68383773 Fax: +86-21-68383699
Received: October 10, 2016
Peer-review started: October 13, 2016
First decision: November 21, 2016
Revised: December 5, 2016
Accepted: December 16, 2016
Article in press: December 19, 2016
Published online: January 21, 2017
Processing time: 95 Days and 15.4 Hours
Peer-review started: October 13, 2016
First decision: November 21, 2016
Revised: December 5, 2016
Accepted: December 16, 2016
Article in press: December 19, 2016
Published online: January 21, 2017
Processing time: 95 Days and 15.4 Hours
Core Tip
Core tip: This is a retrospective study to provide more information and therapeutic methods about gastric neuroendocrine carcinomas. In this study we found that local and/or distant metastases were noticed in most patients when diagnosed, and they required postoperative medical treatment. Adjuvant etoposide, cisplatin plus Paclitaxel systemic chemotherapy is recommended for these patients.