Case Control Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 7, 2017; 23(29): 5356-5363
Published online Aug 7, 2017. doi: 10.3748/wjg.v23.i29.5356
Influence of dietary isoflavone intake on gastrointestinal symptoms in ulcerative colitis individuals in remission
Dominika Głąbska, Dominika Guzek, Dominika Grudzińska, Gustaw Lech
Dominika Głąbska, Dominika Grudzińska, Department of Dietetics, Faculty of Human Nutrition and Consumer Sciences, Warsaw University of Life Sciences (WULS-SGGW), 02-776 Warsaw, Poland
Dominika Guzek, Department of Organization and Consumption Economics, Faculty of Human Nutrition and Consumer Sciences, Warsaw University of Life Sciences (WULS-SGGW), 02-776 Warsaw, Poland
Gustaw Lech, Department of General, Gastroenterological and Oncological Surgery, Medical University of Warsaw, 02-097 Warsaw, Poland
Author contributions: Głąbska D designed the study; Głąbska D, Guzek D, Grudzińska D and Lech G conducted the research; Głąbska D analysed the data and performed the statistical analysis; Głąbska D, Guzek D, Grudzińska D and Lech G wrote the paper; Głąbska D had the primary responsibility for the final content; all authors read and approved the final manuscript.
Supported by Ministry of Science and Higher Education Grant (WULS-SGGW: 505-10-100400-L00332-99/2014)
Institutional review board statement: The study was reviewed and approved by the by the Bioethical Commission of the Central Clinical Hospital of the Ministry of Interior in Warsaw (No 35/ 2009) and the Bioethical Commission of the National Food and Nutrition Institute (No 1604/ 2009).
Informed consent statement: All the participants provided written consent to participate in the study.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dominika Głąbska, PhD, Chair of Dietetics, Department of Dietetics, Faculty of Human Nutrition and Consumer Sciences, Warsaw University of Life Sciences (WULS-SGGW), 159c Nowoursynowska Str, 02-776 Warsaw, Poland. dominika_glabska@sggw.pl
Telephone: + 48-22-5937126 Fax: +48-22-5937018
Received: February 2, 2017
Peer-review started: February 8, 2017
First decision: March 16, 2017
Revised: March 31, 2017
Accepted: May 19, 2017
Article in press: May 19, 2017
Published online: August 7, 2017
Processing time: 186 Days and 7.5 Hours
Core Tip

Core tip: Studies assessing influence of isoflavones on inflammatory bowel disease are contradictory. In presented study a higher daidzein, glycitein and total isoflavones intake in ulcerative colitis individuals in remission were associated with lack of abdominal pain and declared constipations. The effect of isoflavone may be dose-dependent, as in conducted study, an isoflavone intake was over 10 times lower, that in Japanese study, in which it was indicated, that isoflavone intake may be associated with increased risk of the disease. It may be stated, that in European countries, due to lower intake than in Asian ones, beneficial isoflavone effect may be observed.