©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 14, 2017; 23(2): 191-196
Published online Jan 14, 2017. doi: 10.3748/wjg.v23.i2.191
Published online Jan 14, 2017. doi: 10.3748/wjg.v23.i2.191
Evolving strategies for liver fibrosis staging: Non-invasive assessment
Cristina Stasi, Department of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy
Stefano Milani, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, 50134 Florence, Italy
Author contributions: Stasi C and Milani S designed the editorial; Stasi C wrote and revised the manuscript; Milani S critically revised the manuscript for important intellectual content and has given final approval of the version to be published.
Conflict-of-interest statement: The authors declare no financial conflict of interest.
Correspondence to: Cristina Stasi, MD, PhD, Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50141 Firenze, Italy. cristina.stasi@gmail.com
Telephone: +39-55-7947922 Fax: +39-55-7947922
Received: August 25, 2016
Peer-review started: August 27, 2016
First decision: October 10, 2016
Revised: October 22, 2016
Accepted: December 8, 2016
Article in press: December 8, 2016
Published online: January 14, 2017
Processing time: 139 Days and 15.1 Hours
Peer-review started: August 27, 2016
First decision: October 10, 2016
Revised: October 22, 2016
Accepted: December 8, 2016
Article in press: December 8, 2016
Published online: January 14, 2017
Processing time: 139 Days and 15.1 Hours
Core Tip
Core tip: Several studies have demonstrated the accuracy of non-invasive methods to predict significant/advanced fibrosis and cirrhosis and to identify the presence/absence of fibrosis. However, it is still unknown if either non-invasive markers of liver fibrosis or elastography may contribute to a more accurate staging of liver cirrhosis, in terms of prognosis and fibrosis regression after effective therapy. Therefore, future studies are needed to validate non-invasive methods in predicting the different phases of liver cirrhosis.