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World J Gastroenterol. Dec 28, 2016; 22(48): 10523-10531
Published online Dec 28, 2016. doi: 10.3748/wjg.v22.i48.10523
Gastric adenocarcinoma of the fundic gland (chief cell-predominant type): A review of endoscopic and clinicopathological features
Masaki Miyazawa, Mitsuru Matsuda, Masaaki Yano, Yasumasa Hara, Fumitaka Arihara, Yosuke Horita, Koichiro Matsuda, Akito Sakai, Yatsugi Noda
Masaki Miyazawa, Mitsuru Matsuda, Masaaki Yano, Yasumasa Hara, Fumitaka Arihara, Yosuke Horita, Koichiro Matsuda, Akito Sakai, Yatsugi Noda, Department of Internal Medicine, Toyama Prefectural Central Hospital, Toyama 930-8550, Japan
Author contributions: Miyazawa M designed the study and wrote the manuscript; Matsuda M, Yano M, Hara Y, Arihara F, Horita Y, Matsuda K, Sakai A and Noda Y were involved in editing the manuscript.
Conflict-of-interest statement: Authors declare no Conflict of Interests for this article.
Correspondence to: Masaki Miyazawa, MD, Department of Internal Medicine, Toyama Prefectural Central Hospital, 2-2-78 Nishi-Nagae, Toyama, Toyama 930-8550, Japan. miyacchi_1985@yahoo.co.jp
Telephone: +81-76-4241531 Fax: +81-76-4220667
Received: July 27, 2016
Peer-review started: August 6, 2016
First decision: October 10, 2016
Revised: October 27, 2016
Accepted: November 23, 2016
Article in press: November 28, 2016
Published online: December 28, 2016
Processing time: 151 Days and 20.3 Hours
Core Tip

Core tip: Gastric adenocarcinoma of the fundic gland (chief cell-predominant type, GA-FG-CCP) was recently proposed as a novel disease entity. The endoscopic and clinicopathological characteristics of GA-FG-CCP are distinct from those of gastric adenocarcinomas with an intestinal phenotype that originate from the mucosa with chronic gastritis or intestinal metaplasia. Careful endoscopic examination and detailed pathological evaluation are essential for early and accurate diagnosis of GA-FG-CCP.