©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 7, 2016; 22(45): 9966-9973
Published online Dec 7, 2016. doi: 10.3748/wjg.v22.i45.9966
Published online Dec 7, 2016. doi: 10.3748/wjg.v22.i45.9966
Portal hypertension in polycystic liver disease patients does not affect wait-list or immediate post-liver transplantation outcomes
Neil Rajoriya, Dhiraj Tripathi, Joanna A Leithead, Bridget K Gunson, Sophie Lord, James W Ferguson, Gideon M Hirschfield, Liver Unit, Queen Elizabeth Hospital, Birmingham B152WB, United Kingdom
Joanna A Leithead, Bridget K Gunson, Gideon M Hirschfield, Centre for Liver Research, NIHR Birmingham Liver Biomedical Research Unit, University of Birmingham, Birmingham B152TT, United Kingdom
Author contributions: Rajoriya N wrote the manuscript, was involved with project concept and submission; Leithead JA assisted with statistics and discussions of project; Lord S involved with data collection; Ferguson JW and Hirschfield GM involved with project design/concept/review of manuscript; and Tripathi D involved with submission/review of manuscript; all the authors contributed to this manuscript.
Institutional review board statement: The research study was approved by the Queen Elizabeth Hospital, Birmingham local clinical audit committee (Application reference CAB: 04870-12). This paper presents independent research supported by the Birmingham NIHR Liver Biomedical Research Unit based at the University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health.
Informed consent statement: Informed consent was gained from all study participants who were enrolled onto the transplant database.
Conflict-of-interest statement: The authors state no conflict on interest.
Data sharing statement: No additional data are available.
Correspondence to: Gideon M Hirschfield, Professor, Consultant Hepatologist, Centre for Liver Research, NIHR Birmingham Liver Biomedical Research Unit, University of Birmingham, Birmingham B152TT, United Kingdom. g.hirschfield@bham.ac.uk
Telephone: +44-121-4158700 Fax: +44-121-4158701
Received: July 1, 2016
Peer-review started: July 1, 2016
First decision: July 29, 2016
Revised: September 28, 2016
Accepted: November 14, 2016
Article in press: November 16, 2016
Published online: December 7, 2016
Processing time: 158 Days and 22.1 Hours
Peer-review started: July 1, 2016
First decision: July 29, 2016
Revised: September 28, 2016
Accepted: November 14, 2016
Article in press: November 16, 2016
Published online: December 7, 2016
Processing time: 158 Days and 22.1 Hours
Core Tip
Core tip: Clinically apparent portal hypertension is common in patients with polycystic liver disease, however it appears that this finding does not affect wait list or post-transplantation outcomes in the short-term.