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World J Gastroenterol. Sep 14, 2016; 22(34): 7754-7759
Published online Sep 14, 2016. doi: 10.3748/wjg.v22.i34.7754
Sessile serrated adenoma/polyps: Where are we at in 2016?
Rajvinder Singh, Leonardo Zorrón Cheng Tao Pu, Doreen Koay, Alastair Burt
Rajvinder Singh, Gastroenterology Department, Lyell McEwin and Modbury Hospital, NALHN School of Medicine, University of Adelaide, SA 5112, Australia
Leonardo Zorrón Cheng Tao Pu, Gastrointestinal Endoscopy Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-000, Brazil
Leonardo Zorrón Cheng Tao Pu, Gastroenterology Department, Lyell McEwin and Modbury Hospital, University of Adelaide, SA 5000, Australia
Doreen Koay, Gastroenterology Department, Lyell McEwin and Modbury Hospital, University of Adelaide, SA 5000, Australia
Alastair Burt, Executive Dean, Faculty of Health Sciences, University of Adelaide, SA 5000, Australia
Author contributions: Singh R, Koay D and Zorrón Cheng Tao Pu L contributed to this paper with conception and design of the study, literature review and analysis and drafting; all authors contributed with critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Correspondence to: Rajvinder Singh, MBBS, MPhil, FRACP, AM, FRCP, Chair of the AGEA, Director of Gastroenterology, Clinical Associate Professor, Lyell McEwin and Modbury Hospital, NALHN School of Medicine, University of Adelaide, Haydown Road Elizabeth Vale, SA 5112, Australia. rajvinder.singh@sa.gov.au
Telephone: +61-8-81829909 Fax: +61-8-81829837
Received: May 6, 2016
Peer-review started: May 8, 2016
First decision: June 20, 2016
Revised: July 9, 2016
Accepted: July 31, 2016
Article in press: August 1, 2016
Published online: September 14, 2016
Processing time: 124 Days and 14.4 Hours
Core Tip

Core tip: Colorectal cancers (CRC) arise from 3 pathways: adenoma to carcinoma; “Lynch syndrome”; and serrated. There are 3 types of serrated lesions namely: Hyperplastic Polyps, Sessile Serrated Adenomas/Polyps and Traditional Serrated Adenomas, the latter two are associated with CRC. A careful examination of borders, submucosal injection with dye and ensuring that a rim of normal tissue is removed is paramount.