Hashimoto K, Fujiki M, Quintini C, Aucejo FN, Uso TD, Kelly DM, Eghtesad B, Fung JJ, Miller CM. Split liver transplantation in adults. World J Gastroenterol 2016; 22(33): 7500-7506 [PMID: 27672272 DOI: 10.3748/wjg.v22.i33.7500]
Corresponding Author of This Article
Koji Hashimoto, MD, PhD, Department of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave. Desk A-100, Cleveland, OH 44195, United States. hashimk@ccf.org
Research Domain of This Article
Transplantation
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Sep 7, 2016; 22(33): 7500-7506 Published online Sep 7, 2016. doi: 10.3748/wjg.v22.i33.7500
Split liver transplantation in adults
Koji Hashimoto, Masato Fujiki, Cristiano Quintini, Federico N Aucejo, Teresa Diago Uso, Dympna M Kelly, Bijan Eghtesad, John J Fung, Charles M Miller
Koji Hashimoto, Masato Fujiki, Cristiano Quintini, Federico N Aucejo, Teresa Diago Uso, Dympna M Kelly, Bijan Eghtesad, John J Fung, Charles M Miller, Department of General Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH 44195, United States
Author contributions: All authors contributed equally to this work.
Conflict-of-interest statement: The authors declare no conflicts of interest or potential conflicts of interest for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Koji Hashimoto, MD, PhD, Department of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave. Desk A-100, Cleveland, OH 44195, United States. hashimk@ccf.org
Telephone: +1-216-4450753 Fax: +1-216-4449375
Received: March 29, 2016 Peer-review started: April 4, 2016 First decision: May 12, 2016 Revised: May 30, 2016 Accepted: June 28, 2016 Article in press: June 28, 2016 Published online: September 7, 2016 Processing time: 159 Days and 2.1 Hours
Core Tip
Core tip: Split liver transplantation (SLT) in adults is usually performed with the right trisegment graft or less frequently with the hemiliver graft. Both graft types require highly complex surgical techniques. Compared with the right trisegment graft, hemiliver SLT requires stricter donor and recipient selection to prevent graft dysfunction associated with size-mismatch. To achieve ideal graft-recipient paring, a clear understanding of surgical anatomy and recipient physiology is needed. With favorable circumstances, outcomes of adult SLT can be comparable to whole liver transplantation. The routine use of SLT, however, remains controversial due to various challenges, particularly under the current “sickest first” liver allocation policy.
