©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 21, 2016; 22(3): 1311-1320
Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1311
Published online Jan 21, 2016. doi: 10.3748/wjg.v22.i3.1311
Helicobacter pylori associated gastric intestinal metaplasia: Treatment and surveillance
Kevin Sze-Hang Liu, Wai K Leung, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China
Irene Oi-Ling Wong, School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China
Author contributions: Liu KSH, Wong IOL and Leung WK prepared literature review and wrote the paper.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Correspondence to: Wai K Leung, MD, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China. waikleung@hku.hk
Telephone: +852-22553348 Fax: +852-28162863
Received: May 12, 2015
Peer-review started: May 14, 2015
First decision: July 14, 2015
Revised: August 4, 2015
Accepted: November 30, 2015
Article in press: November 30, 2015
Published online: January 21, 2016
Processing time: 248 Days and 5.7 Hours
Peer-review started: May 14, 2015
First decision: July 14, 2015
Revised: August 4, 2015
Accepted: November 30, 2015
Article in press: November 30, 2015
Published online: January 21, 2016
Processing time: 248 Days and 5.7 Hours
Core Tip
Core tip: Gastric intestinal metaplasia (IM) is generally considered to be a pre-neoplastic gastric lesion, which is usually triggered by chronic Helicobacter pylori (H. pylori) infection. However, the role of H. pylori eradication in treating gastric IM remains controversial. It remains uncertain whether the presence of gastric IM signifies an irreversible step of histological progression. Despite the definite increase in risk of gastric cancer development, the role of endoscopic surveillance remains dubious. This review will summarize the latest literature on treatment and surveillance of gastric IM.