©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 7, 2016; 22(1): 1-7
Published online Jan 7, 2016. doi: 10.3748/wjg.v22.i1.1
Published online Jan 7, 2016. doi: 10.3748/wjg.v22.i1.1
Current understanding of the functional roles of aberrantly expressed microRNAs in esophageal cancer
Christine Kestens, Peter D Siersema, Jantine WPM van Baal, Department of Gastroenterology and Hepatology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands
Author contributions: Kestens C reviewed literature, drafted the manuscript; Siersema PD made critical revision; van Baal JWPM contributed to drafting of the manuscript, critical revision.
Conflict-of-interest statement: No potential conflicts of interest.
Correspondence to: Jantine WPM van Baal, PhD, Department of Gastroenterology and Hepatology, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands. j.w.p.m.vanbaal-2@umcutrecht.nl
Telephone: +31-88-7556279 Fax: +31-88-7555081
Received: August 14, 2015
Peer-review started: August 19, 2015
First decision: October 14, 2015
Revised: October 20, 2015
Accepted: November 9, 2015
Article in press: November 9, 2015
Published online: January 7, 2016
Processing time: 248 Days and 11.6 Hours
Peer-review started: August 19, 2015
First decision: October 14, 2015
Revised: October 20, 2015
Accepted: November 9, 2015
Article in press: November 9, 2015
Published online: January 7, 2016
Processing time: 248 Days and 11.6 Hours
Core Tip
Core tip: MicroRNAs (miRNAs) likely have important regulatory roles in the development of cancer as they target essential pathways. Here, we review the function of aberrantly expressed miRNAs in esophageal cancer, with the aim to provide guidelines for future studies focusing on the function of miRNAs and the development of new treatment modalities.