©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 28, 2015; 21(8): 2510-2521
Published online Feb 28, 2015. doi: 10.3748/wjg.v21.i8.2510
Published online Feb 28, 2015. doi: 10.3748/wjg.v21.i8.2510
Prophylactic intra-peritoneal drain placement following pancreaticoduodenectomy: A systematic review and meta-analysis
Yi-Chao Wang, Jing-Qiang Zhu, Department of Thyroid and Breast Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Peter Szatmary, Wei Huang, Ilias Gomatos, Quentin M Nunes, Robert Sutton, NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, L69 3GA Liverpool, United Kingdom
Jun-Jie Xiong, Xu-Bao Liu, Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Wang YC and Szatmary P contributed equally to this work; Zhu JQ, Liu XB and Sutton R designed the research, and corrected and approved the manuscript; Wang YC, Szatmary P, Xiong JJ, Huang W, Gomatos I and Nunes QM developed the literature search and carried out statistical analysis of the studies; Wang YC, Szatmary P, Xiong JJ and Huang W performed data extraction; Wang YC and Szatmary P wrote the manuscript; all authors read and approved the final manuscript.
Correspondence to: Jing-Qiang Zhu, MD, Department of Thyroid and Breast Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Road, Chengdu 610041, Sichuan Province, China. jingqiangzhu@163.com
Telephone: +86-28-85422469 Fax: +86-28-85422872
Received: June 17, 2014
Peer-review started: June 17, 2014
First decision: July 9, 2014
Revised: July 26, 2014
Accepted: September 19, 2014
Article in press: September 19, 2014
Published online: February 28, 2015
Processing time: 256 Days and 0.5 Hours
Peer-review started: June 17, 2014
First decision: July 9, 2014
Revised: July 26, 2014
Accepted: September 19, 2014
Article in press: September 19, 2014
Published online: February 28, 2015
Processing time: 256 Days and 0.5 Hours
Core Tip
Core tip: Routine prophylactic drainage remains standard practice following pancreaticoduodenectomy (PD) due to concerns that abandoning this would not be safe. Existing studies provide limited evidence regarding prophylactic drainage following PD. A systematic review addressing postoperative drainage following PD is therefore required. This study clarified that indiscriminate abandonment of intra-abdominal drainage following PD is associated with greater mortality, but lower overall and major complication rates. However, future randomized trials are needed to compare routine vs selective drainage.