Xu ZJ, Zheng LQ, Pan XN. Partial embolization as re-treatment of hypersplenism after unsuccessful splenic artery ligation. World J Gastroenterol 2015; 21(4): 1365-1370 [PMID: 25632215 DOI: 10.3748/wjg.v21.i4.1365]
Corresponding Author of This Article
Zheng-Ju Xu, Associate Chief Physician, Clinical Liver Center, 180th Hospital of the People’s Liberation Army, No. 180, Huayuan Road, Fengze District, Quanzhou 362000, Fujian Province, China. h180@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Jan 28, 2015; 21(4): 1365-1370 Published online Jan 28, 2015. doi: 10.3748/wjg.v21.i4.1365
Partial embolization as re-treatment of hypersplenism after unsuccessful splenic artery ligation
Zheng-Ju Xu, Lian-Qiu Zheng, Xing-Nan Pan
Zheng-Ju Xu, Lian-Qiu Zheng, Xing-Nan Pan, Clinical Liver Center, 180th Hospital of the People’s Liberation Army, Quanzhou 362000, Fujian Province, China
Author contributions: Xu ZJ conceived and coordinated the study, and participated in data collection and manuscript writing; Pan XN participated in the study design, data collection, and manuscript writing; Zheng LQ participated in data collection and manuscript writing.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Zheng-Ju Xu, Associate Chief Physician, Clinical Liver Center, 180th Hospital of the People’s Liberation Army, No. 180, Huayuan Road, Fengze District, Quanzhou 362000, Fujian Province, China. h180@163.com
Telephone: +86-595-28919590 Fax: +86-595-28919100
Received: June 13, 2014 Peer-review started: June 13, 2014 First decision: July 21, 2014 Revised: August 3, 2014 Accepted: September 12, 2014 Article in press: September 16, 2014 Published online: January 28, 2015 Processing time: 228 Days and 14.3 Hours
Core Tip
Core tip: Ligation of splenic artery (LSA) is used for the treatment of hypersplenism due to liver cirrhosis. However, hypersplenism is not always improved following LSA. We report a case of cirrhosis and hypersplenism which underwent LSA treatment, but failed to respond as manifested by persistent severe leukocytopenia and thrombocytopenia. Celiac computed tomography arteriogram and digital subtraction angiography revealed two compensatory arteries supplying the spleen. Partial splenic embolization (PSE) was performed through those arteries resulting in increased leukocyte and thrombocyte counts that remained within the normal range. PSE is an effective therapeutic modality for the retreatment of hypersplenism when other modalities have failed.
