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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 28, 2015; 21(4): 1207-1215
Published online Jan 28, 2015. doi: 10.3748/wjg.v21.i4.1207
Published online Jan 28, 2015. doi: 10.3748/wjg.v21.i4.1207
Optimal duration of the early and late recurrence of hepatocellular carcinoma after hepatectomy
Yusuke Yamamoto, Hisashi Ikoma, Ryo Morimura, Hirotaka Konishi, Yasutoshi Murayama, Shuhei Komatsu, Atsushi Shiozaki, Yoshiaki Kuriu, Takeshi Kubota, Masayoshi Nakanishi, Daisuke Ichikawa, Hitoshi Fujiwara, Kazuma Okamoto, Chouhei Sakakura, Eigo Otsuji, Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto 6028566, Japan
Toshiya Ochiai, Department of Surgery, North Medical Center, Kyoto Prefectural University of Medicine, Kyoto 6028566, Japan
Author contributions: Yamamoto Y, Ikoma H, Morimura R and Otsuji E designed the research; Yamamoto Y, Ikoma H, Morimura R and Ochiai T performed the research; Yamamoto Y, Konishi H, Murayama Y, Komatsu S, Shiozaki A, Kuriu Y, Kubota T, Nakanishi M, Ichikawa D, Fujiwara H, Okamoto K, Sakakura C and Ochiai T contributed new reagents and analytic tools; Yamamoto Y, Ikoma H, Morimura R and Ochiai T analyzed the data; and Yamamoto Y, Ikoma H and Morimura R wrote the paper.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hisashi Ikoma, MD, Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 6028566, Japan. ikoma@koto.kpu-m.ac.jp
Telephone: +81-75-2515527 Fax: +81-75-2515522
Received: March 16, 2014
Peer-review started: March 17, 2014
First decision: April 5, 2014
Revised: July 16, 2014
Accepted: September 12, 2014
Article in press: September 16, 2014
Published online: January 28, 2015
Processing time: 316 Days and 18.1 Hours
Peer-review started: March 17, 2014
First decision: April 5, 2014
Revised: July 16, 2014
Accepted: September 12, 2014
Article in press: September 16, 2014
Published online: January 28, 2015
Processing time: 316 Days and 18.1 Hours
Core Tip
Core tip: The optimal cut-off value for differentiating early and late recurrence after hepatectomy for the hepatocellular carcinoma based on the overall survival after initial recurrence was 17 mo, and this cut-off may distinguish recurrences with different etiologies.