Karmazanovsky GG, Buryakina SA, Kondratiev EV, Yang Q, Ruchkin DV, Kalinin DV. Value of two-phase dynamic multidetector computed tomography in differential diagnosis of post-inflammatory strictures from esophageal cancer. World J Gastroenterol 2015; 21(29): 8878-8887 [PMID: 26269677 DOI: 10.3748/wjg.v21.i29.8878]
Corresponding Author of This Article
Svetlana A Buryakina, MD, PhD, Department of Radiology, Vishnevsky Institute of Surgery, B. Serpukhovskaya, 27, 117997 Moscow, Russia. sburyakina@yandex.ru
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Retrospective Study
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Karmazanovsky GG, Buryakina SA, Kondratiev EV, Yang Q, Ruchkin DV, Kalinin DV. Value of two-phase dynamic multidetector computed tomography in differential diagnosis of post-inflammatory strictures from esophageal cancer. World J Gastroenterol 2015; 21(29): 8878-8887 [PMID: 26269677 DOI: 10.3748/wjg.v21.i29.8878]
World J Gastroenterol. Aug 7, 2015; 21(29): 8878-8887 Published online Aug 7, 2015. doi: 10.3748/wjg.v21.i29.8878
Value of two-phase dynamic multidetector computed tomography in differential diagnosis of post-inflammatory strictures from esophageal cancer
Grigory G Karmazanovsky, Svetlana A Buryakina, Evgeny V Kondratiev, Qin Yang, Dmitry V Ruchkin, Dmitry V Kalinin
Grigory G Karmazanovsky, Svetlana A Buryakina, Evgeny V Kondratiev, Department of Radiology, Vishnevsky Institute of Surgery, 117997 Moscow, Russia
Qin Yang, Dmitry V Ruchkin, Department of Thoracic Surgery (Esophageal Surgery group), Vishnevsky Institute of Surgery, 117997 Moscow, Russia
Dmitry V Kalinin, Department of Pathomorphology, Vishnevsky Institute of Surgery, 117997 Moscow, Russia
Author contributions: Karmazanovsky GG and Buryakina SA contributed equally to this work; Karmazanovsky GG, Yang Q, Ruchkin DV designed the research; Karmazanovsky GG, Ruchkin DV and Kalinin DV performed the research; Buryakina SA, Kondratiev EV, Kalinin DV analysed the data; Buryakina SA and Kondratiev EV wrote the paper.
Institutional review board statement: The study was reviewed and approved by the ethics committe of Vishnevsky Institute of Surgery, register No. 001a/15.
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There is no conflict of interest.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at sburyakina@yandex.ru. The presented data are anonymized and risk of identification is low. No additional data are available.
Correspondence to: Svetlana A Buryakina, MD, PhD, Department of Radiology, Vishnevsky Institute of Surgery, B. Serpukhovskaya, 27, 117997 Moscow, Russia. sburyakina@yandex.ru
Telephone: +7-499-2373764 Fax: +7-499-2366130
Received: January 26, 2015 Peer-review started: January 27, 2015 First decision: March 10, 2015 Revised: March 25, 2015 Accepted: May 7, 2015 Article in press: May 7, 2015 Published online: August 7, 2015 Processing time: 193 Days and 21 Hours
Core Tip
Core tip: Two-phase dynamic multidetector computed tomography was proposed to evaluate esophageal stenosis. No previous studies have evaluated the utility of this method for post-inflammatory strictures. We investigated this method’s ability to evaluate benign strictures by qualitatively and quantitatively assessing changes in the esophageal walls and demonstrated that the majority of patients with benign strictures had concentric wall thickening with smooth boundaries, conically shaped suprastenotic dilatation, a “target sign”, smooth mucous membrane at the transition to stenosis. An assessment of the dynamics of contrast material accumulation by strictures revealed that the arterial and delayed phases are optimal for differentiating benign strictures from esophageal cancer.
