Al-Hussaini H, Azouz H, Abu-Zaid A. Hepatic inflammatory pseudotumor presenting in an 8-year-old boy: A case report and review of literature. World J Gastroenterol 2015; 21(28): 8730-8738 [PMID: 26229415 DOI: 10.3748/wjg.v21.i28.8730]
Corresponding Author of This Article
Ahmed Abu-Zaid, MBBS, College of Medicine, Alfaisal University, PO Box 50927, Riyadh 11533, Saudi Arabia. aabuzaid@live.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
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Al-Hussaini H, Azouz H, Abu-Zaid A. Hepatic inflammatory pseudotumor presenting in an 8-year-old boy: A case report and review of literature. World J Gastroenterol 2015; 21(28): 8730-8738 [PMID: 26229415 DOI: 10.3748/wjg.v21.i28.8730]
World J Gastroenterol. Jul 28, 2015; 21(28): 8730-8738 Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8730
Hepatic inflammatory pseudotumor presenting in an 8-year-old boy: A case report and review of literature
Hussa Al-Hussaini, Haya Azouz, Ahmed Abu-Zaid
Hussa Al-Hussaini, Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, Saudi Arabia
Haya Azouz, Ahmed Abu-Zaid, College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia
Author contributions: Al-Hussaini H, Azouz H and Abu-Zaid A reviewed the literature and drafted the manuscript; Al-Hussaini H, Azouz H and Abu-Zaid A contributed to the research conception and design, acquired and analyzed the data, and prepared the radiology; Al-Hussaini H prepared all pathology-related figures; all authors edited and revised the manuscript for intellectual content and approved the final version of manuscript.
Institutional review board statement: The publication of this manuscript has been approved by the Research Advisory Council at the King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Informed consent statement: An informed written consent was provided by the boy’s legal guardian (father) to publish this manuscript.
Conflict-of-interest statement: The authors declare no conflicts of interest regarding the production of this article. The authors have no personal financial or institutional interests in any of the drugs, materials, or devices described in this article.
Correspondence to: Ahmed Abu-Zaid, MBBS, College of Medicine, Alfaisal University, PO Box 50927, Riyadh 11533, Saudi Arabia. aabuzaid@live.com
Telephone: +966-11-2157687 Fax: +966-11-2157611
Received: December 17, 2014 Peer-review started: December 17, 2014 First decision: January 22, 2015 Revised: February 22, 2015 Accepted: March 30, 2015 Article in press: March 31, 2015 Published online: July 28, 2015 Processing time: 225 Days and 4.1 Hours
Core Tip
Core tip: Because hepatic inflammatory pseudotumors (IPTs) are considered benign lesions and their natural clinical course advances toward regression, it is extremely critical to establish the most accurate diagnosis and not to regard them as malignant neoplasms that may lead to needless surgical excisions. However, accurately diagnosing hepatic IPTs can be very challenging, likely attributable to the fact that the clinical presentation and radiological appearances are nonspecific and cannot be certainly distinguished from malignant neoplastic processes. Management options include conservative treatment, and if failed, surgical resection. Histopathological and immunohistochemical analysis of the hepatic lesion yields the definitive diagnosis.