Review
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 28, 2015; 21(28): 8541-8561
Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8541
Benign liver tumors in pediatric patients - Review with emphasis on imaging features
Liliana Chiorean, Xin-Wu Cui, Andrea Tannapfel, Doris Franke, Martin Stenzel, Wojciech Kosiak, Dagmar Schreiber-Dietrich, Jörg Jüngert, Jian-Min Chang, Christoph F Dietrich
Liliana Chiorean, Xin-Wu Cui, Dagmar Schreiber-Dietrich, Jian-Min Chang, Christoph F Dietrich, Sino-German Research Center of Ultrasound in Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450001, Henan Province, China
Liliana Chiorean, Christoph F Dietrich, Medical Department 2, Caritas-Krankenhaus, Uhlandstr. 7, D-97980 Bad Mergentheim, Germany
Andrea Tannapfel, Institut für Pathologie, Ruhruniversität Bochum, Georgius Agricola Stiftung Ruhr, Bürkle-de-la-Camp-Platz 1 44789 Bochum, Germany
Doris Franke, Department of Paediatric Kidney, Liver and Metabolic Diseases, Children's Hospital, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany
Jörg Jüngert, Department of Pediatrics, University of Erlangen, Loschgestrasse 15, 91054 Erlangen, Germany
Martin Stenzel, Department of Pediatric Radiology, University of Freiburg, Friedrichstr. 39, 79098 Freiburg, Germany
Wojciech Kosiak, Department of Pediatric Hematology and Oncology, Medical University of Gdansk, 80-210 Gdańsk, Poland
Author contributions: Dietrich CF designed and conceived the paper; Chiorean L, Cui XW, Tannapfel A, Franke D, Stenzel M, Kosiak W, Schreiber-Dietrich D, Jüngert J, Chang JM and Dietrich CF analyzed the literature data; Chiorean L provided the first draft of the manuscript, which was discussed and revised critically for intellectual content by Cui XW, Tannapfel A, Franke D, Stenzel M, Kosiak W, Schreiber-Dietrich D, Jüngert J, Chang JM, and Dietrich CF; all authors discussed the statement and conclusions, and approved the final version to be published.
Conflict-of-interest statement: None to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Christoph F Dietrich, Professor of Medicine, Sino-German Research Center of Ultrasound in Medicine, The First Affiliated Hospital of Zhengzhou University, Jianshe East Road No. 1, Zhengzhou 450052, China. christoph.dietrich@ckbm.de
Telephone: +86-371-66913150 Fax: +86-371-66913150
Received: January 19, 2015
Peer-review started: January 20, 2015
First decision: March 26, 2015
Revised: April 16, 2015
Accepted: May 20, 2015
Article in press: May 21, 2015
Published online: July 28, 2015
Processing time: 192 Days and 11 Hours
Core Tip

Core tip: Focal liver lesions (FLL) are commonly observed in adults, but rarely reported in children. The reasons for this remain speculative. Most benign focal liver lesions are inborn and may grow like the rest of the body. The current paper deals with FLLs in pediatric patients, as well as a comparison to the current knowledge regarding such tumors in adult patients.