©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2015; 21(25): 7929-7932
Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7929
Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7929
Refractory diarrhea: A paraneoplastic syndrome of neuroblastoma
Wei Han, Huan-Min Wang, Oncology Department, Beijing Children’s Hospital, Capital Medical University, Beijing 100045, China
Author contributions: Han W analyzed the data and wrote the paper; Wang HM designed the research and performed the operations.
Ethics approval: The study was reviewed and approved by the Beijing Children’s Hospital Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors have no conflicts of interest to disclose.
Correspondence to: Huan-Min Wang, MD, Oncology Department, Beijing Children’s Hospital, Capital Medical University, No. 56 Nan Lishi Road, Xicheng District, Beijing 100045, China. hamiwang@aliyun.com
Telephone: +86-10-59616413 Fax: +86-10-59718700
Received: January 8, 2015
Peer-review started: January 12, 2015
First decision: March 10, 2015
Revised: April 9, 2015
Accepted: May 21, 2015
Article in press: May 21, 2015
Published online: July 7, 2015
Processing time: 181 Days and 3.2 Hours
Peer-review started: January 12, 2015
First decision: March 10, 2015
Revised: April 9, 2015
Accepted: May 21, 2015
Article in press: May 21, 2015
Published online: July 7, 2015
Processing time: 181 Days and 3.2 Hours
Core Tip
Core tip: Neuroblastoma (NB) is the most common extracranial solid tumor in children. Diarrheal NB is quite rare and is not easy to diagnose in the early stage. Six cases of diarrheal NB were retrospectively analyzed, including characteristics such as electrolyte imbalance, pathologic features, vasoactive intestinal peptide immunohistochemical staining results, treatment, and prognosis.