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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 28, 2015; 21(24): 7488-7494
Published online Jun 28, 2015. doi: 10.3748/wjg.v21.i24.7488
Published online Jun 28, 2015. doi: 10.3748/wjg.v21.i24.7488
Prognostic factors of spontaneously ruptured hepatocellular carcinoma
Xiang-Jun Han, Hong-Ying Su, Hai-Bo Shao, Ke Xu, Department of Radiology, the First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Author contributions: Xu K and Su HY designed the research. Shao HB and Han XJ collected and analyzed the data; Han XJ wrote the paper; all authors read and approved the final manuscript.
Supported by National High-tech Research Foundation of China, No. 2012AA022701.
Ethics approval: This study was approved by the Research Ethics Committee of the First Hospital of China Medical University (Number: 2013-112-2).
Informed consent: All study participants provided written informed consent prior to study enrollment.
Conflict-of-interest: The authors declare that they have no conflicts of interest.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ke Xu, PhD, Department of Radiology, the First Hospital of China Medical University, No.155 North Nanjing Street, Heping District, Shenyang, Liaoning 110001, Liaoning Province, China. xuke1954@sina.com
Telephone: +86-24-83283368 Fax: +86-24-83283368
Received: December 9, 2014
Peer-review started: December 11, 2014
First decision: January 8, 2015
Revised: January 29, 2015
Accepted: February 11, 2015
Article in press: February 11, 2015
Published online: June 28, 2015
Processing time: 202 Days and 1.5 Hours
Peer-review started: December 11, 2014
First decision: January 8, 2015
Revised: January 29, 2015
Accepted: February 11, 2015
Article in press: February 11, 2015
Published online: June 28, 2015
Processing time: 202 Days and 1.5 Hours
Core Tip
Core tip: The most important predictors of survival in patients with spontaneous rupture of hepatocellular carcinoma (HCC) are continuous anti-tumor therapies during the follow-up period, tumor length and number, Barcelona-Clinic Liver Cancer stage, and a history of anti-tumor therapies prior to HCC rupture. Therefore, the present study may provide useful information for doctors making judgments on the prognosis of spontaneously ruptured HCC.