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Wang JZ, Liu Y, Wang JL, Lu L, Zhang YF, Lu HW, Li YM. Sequential vs simultaneous revascularization in patients undergoing liver transplantation: A meta-analysis. World J Gastroenterol 2015; 21(22): 7036-7046 [PMID: 26078582 DOI: 10.3748/wjg.v21.i22.7036]
World J Gastroenterol. Jun 14, 2015; 21(22): 7036-7046 Published online Jun 14, 2015. doi: 10.3748/wjg.v21.i22.7036
Sequential vs simultaneous revascularization in patients undergoing liver transplantation: A meta-analysis
Jia-Zhong Wang, Yang Liu, Jin-Long Wang, Le Lu, Ya-Fei Zhang, Hong-Wei Lu, Yi-Ming Li
Jia-Zhong Wang, Yang Liu, Jin-Long Wang, Le Lu, Ya-Fei Zhang, Hong-Wei Lu, Yi-Ming Li, Department of General Surgery, Second Affiliated Hospital, Xi’an Jiaotong University School of Medicine, Xi’an 710004, Shaanxi Province, China
Author contributions: Li YM and Wang JZ conceived this meta-analysis, wrote the initial manuscript, critically reviewed and revised the manuscript; Wang JZ, Wang JL and Lu L acquired data, performed the initial data analysis; Lu HW critically supervised data acquisition and analysis; and Li YM approved the final version of the manuscript; all authors contributed to this paper.
Supported by National Natural Science Foundation of China, No. 81170454.
Conflict-of-interest: The authors declared that they have no conflicts of interest to this work.
Data sharing: No additional data are available.
Correspondence to: Yi-Ming Li, Professor, Department of General Surgery, Second Affiliated Hospital, Xi’an Jiaotong University School of Medicine, 76 Yanta West Road, Xi’an 710004, Shaanxi Province, China. wjz05202156@stu.xjtu.edu.cn
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Received: November 26, 2014 Peer-review started: November 27, 2014 First decision: December 26, 2014 Revised: January 8, 2015 Accepted: February 5, 2015 Article in press: February 5, 2015 Published online: June 14, 2015 Processing time: 203 Days and 20.5 Hours
Core Tip
Core tip: The current methods of revascularization in liver transplantation can be divided into two main groups. We carried out this meta-analysis in order to study the relationship between revascularization and outcomes after liver transplantation. Ischemic-type biliary lesions were significantly reduced in the simultaneous revascularization group compared with the sequential revascularization group (P < 0.00001), and intensive care unit days were decreased (P = 0.007) in the simultaneous revascularization group. There were no significant differences in other outcomes between sequential and simultaneous revascularization groups, such as blood transfusions, hospital days, graft failure and mortality in one month and one year, operation time.
