Klare P, Ascher S, Hapfelmeier A, Wolf P, Beitz A, Schmid RM, von Delius S. Patient age and duration of colonoscopy are predictors for adenoma detection in both proximal and distal colon. World J Gastroenterol 2015; 21(2): 525-532 [PMID: 25593468 DOI: 10.3748/wjg.v21.i2.525]
Corresponding Author of This Article
Peter Klare, MD, II. Medizinische Klinik, Klinikum rechts der Isar, Technischen Universität München, Ismaninger Str. 22, 81675 Munich, Germany. peter.klare@lrz.tum.de
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
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Klare P, Ascher S, Hapfelmeier A, Wolf P, Beitz A, Schmid RM, von Delius S. Patient age and duration of colonoscopy are predictors for adenoma detection in both proximal and distal colon. World J Gastroenterol 2015; 21(2): 525-532 [PMID: 25593468 DOI: 10.3748/wjg.v21.i2.525]
World J Gastroenterol. Jan 14, 2015; 21(2): 525-532 Published online Jan 14, 2015. doi: 10.3748/wjg.v21.i2.525
Patient age and duration of colonoscopy are predictors for adenoma detection in both proximal and distal colon
Peter Klare, Stefan Ascher, Alexander Hapfelmeier, Petra Wolf, Analena Beitz, Roland M Schmid, Stefan von Delius
Peter Klare, Stefan Ascher, Analena Beitz, Roland M Schmid, Stefan von Delius, II. Medizinische Klinik, Klinikum rechts der Isar, Technischen Universität München, 81675 Munich, Germany
Alexander Hapfelmeier, Petra Wolf, Institut für Medizinische Statistik und Epidemiologie, Klinikum rechts der Isar, Technische Universität München, 81675 Munich, Germany
Author contributions: Klare P and von Delius S carried out the planning of the study, interpretation of the data and preparation of the article; Ascher S and Beitz A carried out the data acquisition; Hapfelmeier A and Wolf P was responsible for the statistical analysis and drafting of the article (Methods section); Schmid RM participated in coordination and helped to draft the article.
Correspondence to: Peter Klare, MD, II. Medizinische Klinik, Klinikum rechts der Isar, Technischen Universität München, Ismaninger Str. 22, 81675 Munich, Germany. peter.klare@lrz.tum.de
Telephone: +49-89-41402251 Fax: +49-89-41404905
Received: May 6, 2014 Peer-review started: May 6, 2014 First decision: May 29, 2014 Revised: July 1, 2014 Accepted: August 28, 2014 Article in press: August 28, 2014 Published online: January 14, 2015 Processing time: 256 Days and 22.1 Hours
Core Tip
Core tip: In this post-hoc study of a prospective randomized trial we analysed the impact of predefined patients and procedural characteristics on adenoma detection. Proximal lesions are at risk for being missed during colonoscopy but data is sparse regarding the existence of specific predictors for the detection of proximal and distal adenomas. Therefore, in our analysis we computed side specific regression analysis in order to define those predictors. Male gender, longer duration of colonoscopy procedure and increasing age were predictors for both proximal and distal adenomas. Proximal adenomas frequently occurred in the absence of distal adenomatous lesions. We therefore suggest total colonoscopy instead of sigmoidoscopy for colorectal cancer screening.
