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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 14, 2015; 21(2): 408-422
Published online Jan 14, 2015. doi: 10.3748/wjg.v21.i2.408
Management of hepatitis C in patients with chronic kidney disease
Maria Lucia G Ferraz, Antonio Eduardo B Silva, Ana Cristina CA Feldner, Roberto J Carvalho-Filho
Roberto J Carvalho-Filho, Ana Cristina CA Feldner, Antonio Eduardo B Silva, Maria Lucia G Ferraz, Division of Gastroenterology, Hepatology Section, Federal University of Sao Paulo, Sao Paulo, SP 04023-900, Brazil
Author contributions: Carvalho-Filho RJ, Feldner ACCA, Silva AEB and Ferraz MLG designed and performed the research, analyzed the data, and wrote the paper; all authors revised and approved the final version.
Correspondence to: Roberto J Carvalho-Filho, MD, Division of Gastroenterology, Hepatology Section, Federal University of Sao Paulo, Rua Botucatu 740, Sao Paulo, SP 04023-900, Brazil. roberto.jcf@gmail.com
Telephone: +55-11-55764050 Fax: +55-11-55729532
Received: July 1, 2014
Peer-review started: July 1, 2014
First decision: July 21, 2014
Revised: September 7, 2014
Accepted: December 8, 2014
Article in press: December 8, 2014
Published online: January 14, 2015
Processing time: 201 Days and 15.9 Hours
Core Tip

Core tip: In this review, we discuss the most recent and relevant literature regarding diagnostic aspects, clinical features, outcomes and therapy of chronic hepatitis C in subjects with chronic kidney disease, in the context of conservative management, hemodialysis, and kidney transplantation. In addition, antiviral regimens are summarized and treatment algorithms are proposed.