©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 21, 2015; 21(11): 3174-3183
Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3174
Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3174
Nuclear factor kappa B role in inflammation associated gastrointestinal malignancies
Sahil Gambhir, Dinesh Vyas, Michael Hollis, Apporva Aekka, Department of Surgery, College of Human Medicine, Michigan State University, East Lansing, MI 48912, United States
Arpita Vyas, Department of Pediatrics, College of Human Medicine - Michigan State University, East Lansing, MI 48912, United States
Author contributions: Gambhir S and Vyas D contributed equally to this work; Gambhir S and Vyas D designed research; analyzed data and wrote the paper; Hollis M contributed in research and editing; Vyas A contributed in data and conceptualization; Aekka A contributed in editing.
Conflict-of-interest: No potential conflicts of interest relevant to this article were reported.
Correspondence to: Dinesh Vyas, MD, MS, FICS, FACS, Department of Surgery, College of Human Medicine, Michigan State University, 1200 East Michigan Avenue, Suite 655, East Lansing, MI 48912, United States. dinesh.vyas@hc.msu.edu
Telephone: +-517-2672491 Fax: +1-517-2672488
Received: June 15, 2014
Peer-review started: June 16, 2014
First decision: August 15, 2014
Revised: August 29, 2014
Accepted: February 12, 2015
Article in press: February 13, 2015
Published online: March 21, 2015
Processing time: 277 Days and 8.7 Hours
Peer-review started: June 16, 2014
First decision: August 15, 2014
Revised: August 29, 2014
Accepted: February 12, 2015
Article in press: February 13, 2015
Published online: March 21, 2015
Processing time: 277 Days and 8.7 Hours
Core Tip
Core tip: Inflammation has a critical role in cancer, its metastasis and angiogenesis. One of the critical mediator is nuclear transcription factor nuclear factor kappa B. This article will be critically useful for basic scientist and clinicians in understanding the the importance of this transcription factor.