Randomized Controlled Trial
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 14, 2015; 21(10): 3041-3048
Published online Mar 14, 2015. doi: 10.3748/wjg.v21.i10.3041
Electrolyte changes after bowel preparation for colonoscopy: A randomized controlled multicenter trial
Kyong Joo Lee, Hong Jun Park, Hyun-Soo Kim, Kwang Ho Baik, Yeon Soo Kim, Sung Chul Park, Hyun Il Seo
Kyong Joo Lee, Hong Jun Park, Hyun-Soo Kim, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju 220-701, South Korea
Kwang Ho Baik, Yeon Soo Kim, Department of Internal Medicine, Hallym University, Chuncheon Sacred Heart Hospital, Chuncheon 200-704, South Korea
Sung Chul Park, Department of Internal Medicine, Kangwon National University Hospital, Chuncheon 200-722, South Korea
Hyun Il Seo, Department of Internal Medicine, Ulsan Medical University, Gangneung Asan Hospital, Gangneung 210-711, South Korea
Author contributions: Lee KJ and Park HJ equally contributed to this work; Park HJ and Kim HS designed the research; Park HJ, Kim HS, Baik KH, Kim YS, Park SC and Seo HI performed endoscopic procedures; Lee KJ and Park HJ analysed the data and wrote the paper; and Kim HS revised the final draft; all authors have read and approved the final manuscript.
Supported by National R and D Program for Cancer Control, Ministry of Health and Welfare, South Korea, No. 1220230; and Taejun Pharmaceutical Company, South Korea.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hyun-Soo Kim, MD, PhD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Ilsanro 20, Wonju City 220-701, Kangwondo, South Korea. hyskim@yonsei.ac.kr
Telephone: +82-33-7411224 Fax: +82-33-7411228
Received: August 4, 2014
Peer-review started: August 5, 2014
First decision: August 27, 2014
Revised: September 29, 2014
Accepted: December 14, 2014
Article in press: December 16, 2014
Published online: March 14, 2015
Processing time: 223 Days and 22 Hours
Core Tip

Core tip: Two-liter polyethylene glycol solution with ascorbic acid (PEG-Asc) is widely used as a bowel preparation solution but few studies concern about electrolytes imbalance, especially for Asian population. In this study, we compared PEG-Asc with 4-L PEG and revealed that there were no significant electrolyte changes after intake of solution in the both groups. In addition, the efficacy of bowel preparation by PEG-Asc was equally effective as 4-L PEG and more patients felt better tolerance in PEG-Asc group. Therefore, PEG-Asc can be better option than 4-L PEG.