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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 14, 2014; 20(30): 10613-10619
Published online Aug 14, 2014. doi: 10.3748/wjg.v20.i30.10613
Published online Aug 14, 2014. doi: 10.3748/wjg.v20.i30.10613
Predictors for failure of stent treatment for benign esophageal perforations - a single center 10-year experience
Saga Persson, Peter Elbe, Ioannis Rouvelas, Mats Lindblad, Koshi Kumagai, Lars Lundell, Magnus Nilsson, Jon A Tsai, Division of Surgery, Karolinska Institutet and GastroCentrum, Department of Clinical Sciences, Intervention and Technology, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden
Author contributions: Tsai JA, Nilsson M, Lindblad M, Lundell L and Rouvelas I designed the research; Persson S, Elbe P and Kumagai K performed the research; Persson S, Tsai JA and Kumagai K analyzed the data; Persson S and Tsai JA wrote the paper.
Correspondence to: Jon A Tsai, MD, PhD, Division of Surgery, Karolinska Institutet and GastroCentrum, Department of Clinical Sciences, Intervention and Technology, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden. jon.tsai@ki.se
Telephone: +46-8-58580000 Fax: +46-8-58582340
Received: August 30, 2013
Revised: December 5, 2013
Accepted: January 8, 2014
Published online: August 14, 2014
Processing time: 352 Days and 20.5 Hours
Revised: December 5, 2013
Accepted: January 8, 2014
Published online: August 14, 2014
Processing time: 352 Days and 20.5 Hours
Core Tip
Core tip: It is unclear to which extent esophageal stenting can heal esophageal perforation-rupture in unselected patients. In this single institution study 83.3% of all benign esophageal perforations/ruptures of mixed etiology, excluding anastomotic leakages, were treated with stent with an intention to heal the perforation, as first-line treatment during a 10-year period. Eighty-two point five percent recovered after stenting and no further intervention was required. Time between perforation and placement of stent emerged as potential risk factor for failure of stenting. The high rate of stenting as primary treatment may have contributed to the relatively low overall in-hospital mortality of 10.4%.