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World J Gastroenterol. May 14, 2014; 20(18): 5461-5473
Published online May 14, 2014. doi: 10.3748/wjg.v20.i18.5461
Published online May 14, 2014. doi: 10.3748/wjg.v20.i18.5461
Helicobacter pylori associated chronic gastritis, clinical syndromes, precancerous lesions, and pathogenesis of gastric cancer development
Jiro Watari, Hirokazu Fukui, Tadayuki Oshima, Toshihiko Tomita, Hiroto Miwa, Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, Japan
Nancy Chen, Peter S Amenta, Kheng-Jim Lim, Kiron M Das, Division of Gastroenterology and Hepatology, Departments of Medicine and Pathology, Robert Wood Johnson Medical School, Rutgers, Cancer Institute of New Jersey, New Brunswick, NJ 08903, United States
Author contributions: Watari J drafted the initial manuscript; Chen N and Lim KJ contributed further and modified sequential draft; Amenta PS provided immunohistochemical interpretation for the various monoclonal antibodies; Das KM critically guided the format and content of the manuscript and revised the paper; all the contributed authors read and approved the final manuscript.
Supported by Grant, NIDDK, RO1DK63618 to KMD from the National Institutes of Health, Bethesda, MD
Correspondence to: Kiron M Das, MD, PhD, Division of Gastroenterology and Hepatology, Departments of Medicine and Pathology, Robert Wood Johnson Medical School, Rutgers, Cancer Institute of New Jersey, 1 Robert Wood Johnson Pl., New Brunswick, NJ 08903, United States. daskm@rwjms.rutgers.edu
Telephone: +81- 732-2357784 Fax: +81-732-2357792
Received: November 2, 2013
Revised: December 12, 2013
Accepted: March 7, 2014
Published online: May 14, 2014
Processing time: 193 Days and 6.5 Hours
Revised: December 12, 2013
Accepted: March 7, 2014
Published online: May 14, 2014
Processing time: 193 Days and 6.5 Hours
Core Tip
Core tip: This review provides a current understanding on Helicobacter pylori, pathogenesis of chronic gastritis, gastric intestinal metaplasia, gastric carcinoma, and prevention strategy.