Saito M, Miyazaki M, Tanino M, Tanaka S, Miyashita K, Izumiyama K, Mori A, Irie T, Tanaka M, Morioka M, Tsukamoto E. 18F-FDG PET/CT imaging for a gastrointestinal mantle cell lymphoma with multiple lymphomatous polyposis. World J Gastroenterol 2014; 20(17): 5141-5146 [PMID: 24803832 DOI: 10.3748/wjg.v20.i17.5141]
Corresponding Author of This Article
Makoto Saito, MD, PhD, Department of Internal Medicine and Hematology, Aiiku Hospital, Chuo-ku, Minami 4 Nishi 25, Sapporo 064-0804, Japan. ikyoku@aiiku-hp.or.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
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Saito M, Miyazaki M, Tanino M, Tanaka S, Miyashita K, Izumiyama K, Mori A, Irie T, Tanaka M, Morioka M, Tsukamoto E. 18F-FDG PET/CT imaging for a gastrointestinal mantle cell lymphoma with multiple lymphomatous polyposis. World J Gastroenterol 2014; 20(17): 5141-5146 [PMID: 24803832 DOI: 10.3748/wjg.v20.i17.5141]
Makoto Saito, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Department of Internal Medicine and Hematology, Aiiku Hospital, Sapporo 064-0804, Japan
Masaya Miyazaki, Mishie Tanino, Shinya Tanaka, Department of Cancer Pathology, Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan
Kencho Miyashita, Department of Gastroenterology, Aiiku Hospital, Sapporo 064-0804, Japan
Eriko Tsukamoto, Department of Nuclear Medicine, Central CI Clinic, Sapporo 060-0042, Japan
Author contributions: Saito M, Izumiyama K, Mori A, Irie T, Tanaka M and Morioka M collected the patient’s clinical data; Saito M and Miyashita K analyzed the endoscopic features; Tsukamoto E interpreted the 18F-FDG PET/CT imaging; Miyazaki M, Tanino M and Tanaka S performed the pathological analyses including evaluation of the Ki-67 proliferative index; Saito M designed and wrote the report.
Supported by Department of Cancer Pathology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Correspondence to: Makoto Saito, MD, PhD, Department of Internal Medicine and Hematology, Aiiku Hospital, Chuo-ku, Minami 4 Nishi 25, Sapporo 064-0804, Japan. ikyoku@aiiku-hp.or.jp
Telephone: +81-11-5632211 Fax: +81-11-5221691
Received: October 12, 2013 Revised: January 10, 2014 Accepted: March 7, 2014 Published online: May 7, 2014 Processing time: 206 Days and 18.9 Hours
Core Tip
Core tip: To the present, there have been no reports on [fluorine-18]-fluorodeoxy-glucose (18F-FDG)-positron emission tomography (PET)/computed tomography (CT) imaging of gastrointestinal mantle cell lymphoma (MCL) with multiple lymphomatous polyposis (MLP). In this report, we present the results of 18F-FDG PET/CT imaging in such a MCL patient showing continuous MLP from the stomach to the rectum. We also compared FDG-PET/CT imaging with the Ki-67 proliferative index, an index of cell proliferation, and found that their relationship was inconsistent. The findings of FDG-PET/CT were false negative in typical MLP, but uptake was noted in larger lesions with deep infiltration considered atypical MLP, regardless of the Ki-67 proliferative index.
