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World J Gastroenterol. Apr 7, 2014; 20(13): 3716-3718
Published online Apr 7, 2014. doi: 10.3748/wjg.v20.i13.3716
Published online Apr 7, 2014. doi: 10.3748/wjg.v20.i13.3716
Ulcerative colitis flair induced by mesalamine suppositories hypersensitivity
Hao Ding, Xiao-Chang Liu, Qiao Mei, Jian-Ming Xu, Jing Hu, Department of Gastroenterology, First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Xiang-Yang Hu, Department of Pathology, First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Author contributions: Ding H and Liu XC contributed equally to this work; Ding H and Liu XC drafted the paper under the close supervision of Mei Q; Xu JM and Hu J participated in the design and coordination of the study; Hu XY performed the pathological examination.
Correspondence to: Qiao Mei, MD, Department of Gastroenterology, First Affiliated Hospital of Anhui Medical University, No. 218, Jixi Road, Hefei 230022, Anhui Province, China. meiqiao@hotmail.com
Telephone: +86-551-62922039 Fax: +86-551-62922039
Received: September 15, 2013
Revised: November 5, 2013
Accepted: December 12, 2013
Published online: April 7, 2014
Processing time: 200 Days and 16.3 Hours
Revised: November 5, 2013
Accepted: December 12, 2013
Published online: April 7, 2014
Processing time: 200 Days and 16.3 Hours
Core Tip
Core tip: Mesalamine suppository, a kind of newly designed 5-aminosalicylic acid formulations, is considered safe and effective and is widely used in the treatment of distal ulcerative colitis. Few cases concerning its side effect of hypersensitivity have been reported. Herein, we report a case of ulcerative colitis flare induced by mesalamine suppository hypersensitivity in an attempt to improve our understandings of the rare side effect of mesalamine suppositories.