Kudo T, Kawakami H, Kuwatani M, Eto K, Kawahata S, Abe Y, Onodera M, Ehira N, Yamato H, Haba S, Kawakubo K, Sakamoto N. Influence of the safety and diagnostic accuracy of preoperative endoscopic ultrasound-guided fine-needle aspiration for resectable pancreatic cancer on clinical performance. World J Gastroenterol 2014; 20(13): 3620-3627 [PMID: 24707146 DOI: 10.3748/wjg.v20.i13.3620]
Corresponding Author of This Article
Hiroshi Kawakami, MD, PhD, Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan. hiropon@med.hokudai.ac.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Research Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Apr 7, 2014; 20(13): 3620-3627 Published online Apr 7, 2014. doi: 10.3748/wjg.v20.i13.3620
Influence of the safety and diagnostic accuracy of preoperative endoscopic ultrasound-guided fine-needle aspiration for resectable pancreatic cancer on clinical performance
Taiki Kudo, Hiroshi Kawakami, Masaki Kuwatani, Kazunori Eto, Shuhei Kawahata, Yoko Abe, Manabu Onodera, Nobuyuki Ehira, Hiroaki Yamato, Shin Haba, Kazumichi Kawakubo, Naoya Sakamoto, Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan
Author contributions: Kudo T and Kawakami H contributed equally to this work; Kawakami H managed the patient, performed the endoscopic examination, designed the research and provided discussion; Kudo T and Kawakami H analysed the data; Kuwatani M, Eto K, Kawahata S, Abe Y, Onodera M, Ehira N, Yamato H, Haba S and Kawakubo K collected the data and provided clinical advice; Kudo T and Kawakami H collected the data and wrote the paper; Kawakami H and Kuwatani M revised the paper; Sakamoto N supervised the research; all authors approved the final manuscript for publication.
Correspondence to: Hiroshi Kawakami, MD, PhD, Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan. hiropon@med.hokudai.ac.jp
Received: October 3, 2013 Revised: December 1, 2013 Accepted: January 3, 2014 Published online: April 7, 2014 Processing time: 182 Days and 19.6 Hours
Core Tip
Core tip: Whether preoperative endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is safe and effective for resectable pancreatic cancer has not yet been established. In the present study, patients who underwent EUS-FNA had better relapse-free survival and overall survival than did those who did not, although it should be noted that more patients in the FNA before surgery group received adjuvant chemotherapy. Our findings suggest that preoperative EUS-FNA does not adversely affect surgery or prognosis in patients with resectable pancreatic cancer. EUS-FNA can also potentially reduce the inappropriate performance of pancreatic surgery by facilitating an accurate diagnosis. These findings are important because the use of preoperative EUS-FNA is becoming more widespread.
