Bian Y, Wang L, Chen C, Lu JP, Fan JB, Chen SY, Zhao BH. Quantification of pancreatic exocrine function of chronic pancreatitis with secretin-enhanced MRCP. World J Gastroenterol 2013; 19(41): 7177-7182 [PMID: 24222963 DOI: 10.3748/wjg.v19.i41.7177]
Corresponding Author of This Article
Li Wang, MD, Department of Radiology, Changhai Hospital, the Second Military Medical University, 168 Changhai Road, Shanghai 200433, China. wangli_changhai@163.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Brief Article
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Yun Bian, Li Wang, Chao Chen, Jian-Ping Lu, Jia-Bao Fan, Shi-Yue Chen, Bing-Hui Zhao, Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China
Jia-Bao Fan, Department of laboratory, the 411st Hospital of Chinese PLA, Shanghai 200081, China
Author contributions: Bian Y performed the majority of experiments; Wang L, Chen C and Lu JP provided vital reagents and analytical tools and were also involved in editing the manuscript; Fan JB, Chen SY, Zhao BH provided the technical support; Bian Y wrote the manuscript.
Correspondence to: Li Wang, MD, Department of Radiology, Changhai Hospital, the Second Military Medical University, 168 Changhai Road, Shanghai 200433, China. wangli_changhai@163.com
Telephone: +86-13-816357024 Fax: +86-21-65254525
Received: July 27, 2013 Revised: September 4, 2013 Accepted: September 15, 2013 Published online: November 7, 2013 Processing time: 112 Days and 18 Hours
Core Tip
Core tip: After all subjects were injected secretin, the results of secretin enhanced magnetic resonance cholangiopancreatography (SMRCP) were that the mean values of PFR and PT were 8.18 ± 1.11 mL/min, 5.76 ± 1.71 min for normal; 7.27 ± 2.04 mL/min, 7.71 ± 2.55 min for mild chronic pancreatitis (CP); 4.98 ± 2.57 mL/min, 9.10 ± 3.00 min for moderate CP; 4.13 ± 1.83 mL/min, 12.33 ± 1.55 min for advanced CP. Statistically significant difference in PFR and PT was observed between health and CP. Also, there was correlation and consistency between Quantification of secretin enhanced magnetic resonance cholangiopancreatography and enzyme-linked immunosorbent assay test. SMRCP can provide a safe, non-invasive and efficient method to evaluate the exocrine function of the pancreas.
