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World J Gastroenterol. Nov 28, 2011; 17(44): 4858-4866
Published online Nov 28, 2011. doi: 10.3748/wjg.v17.i44.4858
Published online Nov 28, 2011. doi: 10.3748/wjg.v17.i44.4858
Erlotinib inhibits progression to dysplasia in a colitis-associated colon cancer model
Beatriz Pagán, Angel A Isidro, Myrella L Cruz, Caroline B Appleyard, Department of Physiology and Pharmacology, Ponce School of Medicine, Ponce, PR 00732, United States
Yuan Ren, Jie Wu, Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, United States
Domenico Coppola, Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, United States
Author contributions: Appleyard CB, Wu J and Pagán B designed the research; Pagán B, Cruz ML and Ren Y performed the research; Pagán B, Isidro AA, Cruz ML, Coppola D, Appleyard CB and Wu J analyzed the data; Pagán B, Appleyard CB and Wu J wrote the paper.
Supported by National Institutes of Health Grants, No. U56 CA126379 (to Isidro AA and Appleyard CB), No. CA118809 (to Wu J); and a National Institutes of Health Predoctoral Fellowship No. F31 GM078951 (to Pagán B)
Correspondence to: Caroline B Appleyard, PhD, Professor, Department of Physiology and Pharmacology, Ponce School of Medicine, PO Box 7004, Ponce, PR 00732, United States.cappleyard@psm.edu
Telephone: +1-787-8402575 Fax: +1-787-8411040
Received: June 8, 2011
Revised: August 21, 2011
Accepted: October 14, 2011
Published online: November 28, 2011
Revised: August 21, 2011
Accepted: October 14, 2011
Published online: November 28, 2011
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