Zhang J, Gao LC, Guo S, Mei TL, Zhou J, Wang GL, Yu FH, Fang YL, Xu BP. Endoscopic retrograde cholangiopancreatography in the treatment of pancreaticopleural fistula in children. World J Gastroenterol 2020; 26(37): 5718-5730 [PMID: 33088164 DOI: 10.3748/wjg.v26.i37.5718]
Corresponding Author of This Article
Jing Zhang, MD, Chief Physician, Department of Gastroenterology, Beijing Children’s Hospital, Capital Medical University, National Center for Children's Health, No. 56 Nanlishi Road, Xicheng District, Beijing 100045, China. zhjtg666@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Evidence-Based Medicine
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Oct 7, 2020; 26(37): 5718-5730 Published online Oct 7, 2020. doi: 10.3748/wjg.v26.i37.5718
Endoscopic retrograde cholangiopancreatography in the treatment of pancreaticopleural fistula in children
Jing Zhang, Liu-Cun Gao, Shu Guo, Tian-Lu Mei, Jin Zhou, Guo-Li Wang, Fei-Hong Yu, Yong-Li Fang, Bao-Ping Xu
Jing Zhang, Shu Guo, Tian-Lu Mei, Jin Zhou, Guo-Li Wang, Fei-Hong Yu, Yong-Li Fang, Department of Gastroenterology, Beijing Children’s Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China
Liu-Cun Gao, Clinical Research Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China
Bao-Ping Xu, China National Clinical Research Center of Respiratory Diseases, Department of Respiratory, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing 100045, China
Author contributions: Zhang J, Gao LC, Guo S, Mei TL, Zhou J, Wang GL, Yu FH, Fang YL, and Xu BP wrote and revised the manuscript.
Conflict-of-interest statement: There are no conflicts of interest arising from this work.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jing Zhang, MD, Chief Physician, Department of Gastroenterology, Beijing Children’s Hospital, Capital Medical University, National Center for Children's Health, No. 56 Nanlishi Road, Xicheng District, Beijing 100045, China. zhjtg666@163.com
Received: May 31, 2020 Peer-review started: May 31, 2020 First decision: June 18, 2020 Revised: July 1, 2020 Accepted: September 15, 2020 Article in press: September 15, 2020 Published online: October 7, 2020 Processing time: 119 Days and 14.5 Hours
ARTICLE HIGHLIGHTS
Research background
Pancreaticopleural fistula (PPF) can be diagnosed by laboratory examination and imaging examination. The traditional treatments are conservative treatment and surgery. Endoscopic retrograde cholangiopancreatography (ERCP) has since been performed increasingly more often in the diagnosis and treatment of PPF in adults. However, the experience of ERCP in the treatment of PPF in children is limited.
Research motivation
In the present study, the clinical data of children with PPF diagnosed in Beijing Children’s Hospital were retrospectively analyzed, and the children’s therapeutic response to ERCP was explored by comparison with previous publications worldwide.
Research objectives
This study is aimed to explore the treatment response to ERCP for PPF in children.
Research methods
Data on the clinical characteristics, diagnosis, treatments, and outcomes of seven Chinese children with PPF were analyzed and compared with those described in previous publications of children and adults with PPF worldwide.
Research results
There was no significant difference in the postoperative hospital stays between surgical treatment and ERCP. However, there was a positive linear correlation between the overall hospital stay and ERCP intervention time.
Research conclusions
ERCP is recommended as the first-choice treatment of PPF in children. ERCP should be performed as early as possible if conditions permit.
Research perspectives
Because PPF is a rare disease and it is difficult to obtain data on clinical cases, the present study included only seven patients, one of whom was lost to follow-up after discharge. Thus, we were unable to perform a scientific and systematic comparative analysis on the curative effect of surgery and ERCP. The conclusions of this study still need to be validated.
