Clinical Trials Study
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 28, 2018; 24(32): 3671-3676
Published online Aug 28, 2018. doi: 10.3748/wjg.v24.i32.3671
Vascular anatomy of inferior mesenteric artery in laparoscopic radical resection with the preservation of left colic artery for rectal cancer
Ke-Xin Wang, Zhi-Qiang Cheng, Zhi Liu, Xiao-Yang Wang, Dong-Song Bi
Ke-Xin Wang, Zhi-Qiang Cheng, Zhi Liu, Xiao-Yang Wang, Dong-Song Bi, Department of General Surgery, Qilu Hospital of Shandong University, Jinan 250012, Shandong Province, China
Author contributions: Wang KX and Bi DS designed the study and wrote the manuscript; Wang KX and Liu Z instructed the whole study and prepared the figures; Wang KX and Wang XY collected and analyzed the data; Wang KX, Cheng ZQ, Liu Z, and Bi DS performed the operations; all authors have approved the final version of the manuscript.
Supported by the National Natural Science Foundation of China, No. 81471020; Shandong Medical and Health Technology Development Project, No. 2014WS0148; Qilu Hospital of Shandong University Scientific Research Funding, No. 2015QLMS32; and Shandong University Basic Scientific Research Funding (Qilu Hospital Clinical Research Project), No. 2014QLKY21.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Qilu Hospital of Shandong University.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors declare there are no competing interests in this study.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The experimental method of this study was not a randomized controlled trial.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dong-Song Bi, PhD, Chief Doctor, Professor, Surgeon, Department of General Surgery, Qilu Hospital of Shandong University, 107#, Wenhua Xi Road, Jinan 250012, Shandong Province, China. bds20180512@sina.com
Telephone: +86-531-82165252 Fax: +86-531-82165252
Received: June 27, 2018
Peer-review started: July 2, 2018
First decision: July 11, 2018
Revised: July 17, 2018
Accepted: July 22, 2018
Article in press: July 21, 2018
Published online: August 28, 2018
Processing time: 61 Days and 22.7 Hours
ARTICLE HIGHLIGHTS
Research background

In laparoscopic radical resection for rectal cancer, according to the location of the tie of the inferior mesenteric artery (IMA), it is divided into the high-tie of the IMA at its origin and the low-tie of the IMA below the branch into the left colic artery (LCA) with preservation of the LCA. Currently, there is still controversy regarding the indications for high-tie or low-tie approaches.

Research motivation

In laparoscopic radical resection for rectal cancer, high-tie of the IMA at its origin is essential for en bloc lymph node dissection. We studied the vascular anatomy of the IMA to safely and effectively dissect the lymph nodes around the IMA while preserving the LCA in a laparoscopic procedure for rectal cancer.

Research objectives

We aimed to investigate the vascular anatomy of IMA in laparoscopic radical resection with the preservation of LCA for rectal cancer.

Research methods

The records of 110 patients, who underwent laparoscopic surgical resection with preservation of the LCA for rectal cancer from March 2016 to November 2017 were retrospectively analyzed. The research participants were recruited from the Department of General Surgery of Qilu Hospital, a teaching hospital of Shandong University in Shandong, China. A 3D vascular reconstruction was performed before each surgical procedure to assess the branches of the IMA. During surgery, the relationship among the IMA, LCA, sigmoid artery (SA) and superior rectal artery (SRA) was evaluated.

Research results

IMA, LCA, SA, and SRA were studied in 110 cases by preoperative 3D reconstruction of the vascular anatomy and laparoscopic surgery. Three vascular types were identified in the study: type A, LCA arose independently from the IMA (46.4%, n = 51); type B, LCA and SA branched from a common trunk of the IMA (23.6%, n = 26); and type C, LCA, SA, and SRA branched at the same location (30.0%, n = 33). There was no statistically significant difference in the length from the origin of the IMA to the LCA among the three types. In laparoscopic surgery, the LCA was located under the IMV in 61 cases and above the IMV in 49 cases. The ratio regarding the location of the LCA under the IMV in the three types was similar. The data of operating time, blood loss, and the length of postoperative hospital stay were not statistically significant among the three types. Additionally, there were no statistically significant differences in the dissected lymph node numbers. The incidence of metastasis to station 253 nodes was 4.5% (5 of 110). The postoperative complications included anastomotic bleeding in two cases and anastomotic leakage in two cases.

Research conclusions

Knowledge of the anatomy of the branch vessels originating from the IMA and the relationship between the IMA and IMV are essential in order to conduct a laparoscopic radical resection with preservation of the LCA for rectal cancer. To recognize the different branches of the IMA is necessary for the resection of lymph nodes and dissection of vessels.

Research perspectives

We studied the vascular anatomy of the IMA to safely and effectively dissect the lymph nodes around the IMA while preserving the LCA in a laparoscopic procedure for rectal cancer. However, in the light of the limited evidence, the clinical benefit needs more high-quality RCT studies.